000135864 001__ 135864
000135864 005__ 20240621122512.0
000135864 037__ $$aTESIS-2024-268
000135864 041__ $$aeng
000135864 1001_ $$aZárate Roldán, Silvia Stephany
000135864 24500 $$aAdvancements in new catalytic methods for the synthesis of valuable organic compounds
000135864 260__ $$aZaragoza$$bUniversidad de Zaragoza, Prensas de la Universidad$$c2024
000135864 300__ $$a300
000135864 4900_ $$aTesis de la Universidad de Zaragoza$$v2024-260$$x2254-7606
000135864 500__ $$aPresentado: 21 03 2024
000135864 502__ $$aTesis-Univ. Zaragoza, , 2024$$bZaragoza, Universidad de Zaragoza$$c2024
000135864 506__ $$aby-nc$$bCreative Commons$$c3.0$$uhttp://creativecommons.org/licenses/by-nc/3.0/es
000135864 520__ $$aThe thesis focuses on various methodologies in organic chemistry, specifically homogeneous catalysis, explored across multiple chapters. One chapter investigates using gold catalysis to synthesize propargylamines and oxidize aldehydes without direct manipulation. It likely includes an analysis of reaction pathways and mechanism insights. Additionally, it discusses biological applications using different propargylamines coordinated with gold complexes, calculating IC50. <br />Another chapter extends the scope to encompass the alkylation of nucleophilic derivatives using various substrates, such as alcohols, amides, hydrazides, etc. The chapter analyzes reaction conditions and substrate compatibility and delves into Friedel-Crafts alkylation of indoles within deep eutectic solvents. It examines the advantages of deep eutectic solvents over traditional solvents and likely includes discussions on reaction mechanisms and conditions influencing selectivity. <br />The final chapter concentrates on chiral DES for aldol reactions, utilizing L-proline and glycols as catalysts to achieve high enantioselectivity and diastereomeric ratio. This section delves into synthetic applications and potential mechanistic pathways. Throughout the thesis, detailed experimental procedures, characterization data, and mechanistic insights are provided, supported by pertinent literature. The integration of graphical representations enhances the clarity and comprehension of the research findings.<br />
000135864 520__ $$a<br />
000135864 521__ $$97082$$aPrograma de Doctorado en Química Orgánica
000135864 540__ $$9info:eu-repo/semantics/embargoedAccess
000135864 6531_ $$aquímica orgánica
000135864 6531_ $$acatálisis
000135864 691__ $$a4 9 12
000135864 692__ $$aGarantizar una educación de calidad inclusiva y equitativa, y promover las oportunidades de aprendizaje permanente para todos. Desarrollar infraestructuras resilientes, promover la industrialización inclusiva y sostenible, y fomentar la innovación. Garantizar las pautas de consumo y de producción sostenibles.
000135864 700__ $$aGimeno Floría, María Concepción$$edir.
000135864 700__ $$aPérez Herrera, Raquel $$edir.
000135864 7102_ $$aUniversidad de Zaragoza$$b
000135864 830__ $$9494
000135864 8560_ $$fcdeurop@unizar.es
000135864 8564_ $$s14512014$$uhttps://zaguan.unizar.es/record/135864/files/TESIS-2024-268.pdf$$zinfo:eu-repo/date/embargoEnd/2026-03-21
000135864 909CO $$ooai:zaguan.unizar.es:135864$$pdriver
000135864 909co $$ptesis
000135864 9102_ $$aCiencias$$b
000135864 980__ $$aTESIS