000136013 001__ 136013 000136013 005__ 20240704095850.0 000136013 0247_ $$2doi$$a10.1016/j.talanta.2024.126210 000136013 0248_ $$2sideral$$a139013 000136013 037__ $$aART-2024-139013 000136013 041__ $$aeng 000136013 100__ $$aBolea-Fernández, Eduardo 000136013 245__ $$aDevelopment and initial evaluation of a combustion-based sample introduction system for direct isotopic analysis of mercury in solid samples via multi-collector ICP-mass spectrometry 000136013 260__ $$c2024 000136013 5203_ $$aHigh-precision isotopic analysis of mercury (Hg) using multi-collector ICP-mass spectrometry (MC-ICP-MS) is a powerful method for obtaining insight into the sources, pathways and sinks of this toxic metal. Modification of a commercially available mercury analyzer (Teledyne Leeman Labs, Hydra IIc – originally designed for quantification of Hg through sample combustion, collection of the Hg vapor on a gold amalgamator, subsequent controlled release of Hg and detection using cold vapor atomic absorption spectrometry CVAAS) enabled the system to be used for the direct high-precision Hg isotopic analysis of solid samples using MC-ICP-MS – i.e., without previous sample digestion and subsequent dilution. The changes made to the mercury analyzer did not compromise its (simultaneous) use for Hg quantification via CVAAS. The Hg vapor was mixed with a Tl-containing aerosol produced via pneumatic nebulization, creating wet plasma conditions, and enabling the use of Tl as an internal standard for correction of instrumental mass discrimination. Accurate and precise (0.10 ‰ 2SD, δ202Hg, n = 5) results were obtained for an in-house standard solution of Hg (20 ng Hg sample intake). Initial validation relied on the successful analysis of two solid certified reference materials of biological origin (BCR CRM 464 Tuna fish and NRC-CNRC TORT-3 Lobster hepatopancreas). It was shown that instrumental mass discrimination can be adequately corrected for by relying on the use of an aqueous Hg standard solution (NIST SRM 3133), without the need of matrix-matching. The novel setup developed thus allows for direct high-precision isotopic analysis of Hg in solid samples, thus enhancing the sample throughput. It is also suited for samples for which low amounts are available only and/or that are characterized by low Hg concentrations. 000136013 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E43-20R$$9info:eu-repo/grantAgreement/EC/H2020/101034288/EU/International Fellowship Programme for Talent Attraction to the Campus of International Excellence Campus Iberus/IberusExperience$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 101034288-IberusExperience$$9info:eu-repo/grantAgreement/ES/MICINN/PID2021-122455NB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/RYC2021-031093-I 000136013 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000136013 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000136013 700__ $$aRua-Ibarz, Ana 000136013 700__ $$aAnjos, Jorge Alves 000136013 700__ $$aVanhaecke, Frank 000136013 773__ $$g276 (2024), 126210 [7 pp.]$$pTalanta$$tTalanta$$x0039-9140 000136013 8564_ $$s2924906$$uhttps://zaguan.unizar.es/record/136013/files/texto_completo.pdf$$yVersión publicada 000136013 8564_ $$s2448099$$uhttps://zaguan.unizar.es/record/136013/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000136013 909CO $$ooai:zaguan.unizar.es:136013$$particulos$$pdriver 000136013 951__ $$a2024-07-04-08:00:09 000136013 980__ $$aARTICLE