000136296 001__ 136296
000136296 005__ 20240731105612.0
000136296 0247_ $$2doi$$a10.1016/j.bbr.2024.115140
000136296 0248_ $$2sideral$$a139236
000136296 037__ $$aART-2024-139236
000136296 041__ $$aeng
000136296 100__ $$aPérez, Vanesa
000136296 245__ $$aIndividual posterior alpha rhythms and cognitive reserve as possible early prognostic markers in people with subjective memory complaints
000136296 260__ $$c2024
000136296 5060_ $$aAccess copy available to the general public$$fUnrestricted
000136296 5203_ $$aSubjective memory complaints (SMCs) are a memory disorder that often precedes mild cognitive impairment (MCI) or Alzheimer’s disease (AD). Both individual alpha rhythms and cognitive reserve (CR) represent key features of SMCs and provide useful tools to characterize and predict the course of the disorder. We studied whether older people with SMCs may also present some abnormal resting state electroencephalogram (rsEEG) alpha rhythms, and whether alpha rhythms are associated with CR. To do this, eyes-closed rsEEG were recorded in 68 older people with and without SMCs. The individual alpha indexes alpha/theta transition frequency (TF) and individual alpha frequency peak (IAFp) were computed. TF and IAFp were also used to determine the alpha1, alpha2, and alpha3 power frequency. Results indicated no differences in TF or IAFp between older people with SMCs and controls. The SMCs group showed a reduction in alpha3 power in comparison with controls. Specifically, women with SMCs were characterized by a significant decrease in alpha3 power compared to control women. Furthermore, only in SMCs group, greater CR was associated with slow IAFp. In sum, these results suggest that TF and IAFp are two stable indexes that are not influenced by the presence of SMCs. However, the reduction in alpha3, as observed in women with SMCs, shows an abnormal posterior rsEEG at alpha power. Finally, the compensatory mechanisms of CR appear to interact with the neurophysiological mechanisms that underlie the regulation of alpha rhythms.
000136296 536__ $$9Info:eu-repo/grantAgreement/ES/AEI/PID2020-119406GB-I00$$9info:eu-repo/grantAgreement/ES/DGA/S31-23R
000136296 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000136296 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000136296 700__ $$0(orcid)0000-0003-3920-1099$$aHidalgo, Vanesa$$uUniversidad de Zaragoza
000136296 700__ $$aSalvador, Alicia
000136296 7102_ $$14009$$2725$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicobiología
000136296 773__ $$g471 (2024), 115140 [7 pp.]$$pBehav. brain res.$$tBehavioural brain research$$x0166-4328
000136296 8564_ $$s1494310$$uhttps://zaguan.unizar.es/record/136296/files/texto_completo.pdf$$yVersión publicada
000136296 8564_ $$s2620285$$uhttps://zaguan.unizar.es/record/136296/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000136296 909CO $$ooai:zaguan.unizar.es:136296$$particulos$$pdriver
000136296 951__ $$a2024-07-31-09:22:27
000136296 980__ $$aARTICLE