136332 20260217205533.0 doi 10.1093/ecco-jcc/jjad184 sideral 139315 ART-2024-139315 eng Casas Deza, Diego Universidad de Zaragoza (orcid)0000-0001-6883-8940 Initial Management of Intra-abdominal Abscesses and Preventive Strategies for Abscess Recurrence in Penetrating Crohn’s Disease: A National, Multicentre Study Based on ENEIDA Registry 2024 Introduction Intra-abdominal abscesses complicating Crohn’s disease [CD] are a challenging situation. Their management, during hospitalisation and after resolution, is still unclear. Methods Adult patients with CD complicated with intra-abdominal abscess. who required hospitalisation, were included from the prospectively maintained ENEIDA registry from GETECCU. Initial strategy effectiveness and safety to resolve abscess was assessed. Survival analysis was performed to evaluate recurrence risk. Predictive factors associated with resolution were evaluated by multivariate regression and predictive factors associated with recurrence were assessed by Cox regression. Results In all, 520 patients from 37 Spanish hospitals were included; 322 [63%] were initially treated with antibiotics alone, 128 [26%] with percutaneous drainage, and 54 [17%] with surgical drainage. The size of the abscess was critical to the effectiveness of each treatment. In abscesses < 30 mm, the antibiotic was as effective as percutaneous or surgical drainage. However, in larger abscesses, percutaneous or surgical drainage was superior. In abscesses > 50 mm, surgery was superior to percutaneous drainage, although it was associated with a higher complication rate. After abscess resolution, luminal resection was associated with a lower 1-year abscess recurrence risk [HR 0.43, 95% CI 0.24-0.76]. However, those patients who initiated anti-TNF therapy had a similar recurrence risk whether luminal resection had been performed. Conclusions Small abscesses [<30mm] can be managed with antibiotics alone; larger ones require drainage. Percutaneous drainage will be effective and safer than surgery in many cases. After discharge, anti-TNF therapy reduces abscess recurrence risk in a similar way to bowel resection. info:eu-repo/grantAgreement/ES/ISCIII-FEDER/CM21-00067 info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 8.7 2024 GASTROENTEROLOGY & HEPATOLOGY 12 / 148 = 0.081 2024 Q1 T1 2.991 2024 Medicine (miscellaneous) 2024 Q1 Gastroenterology 2024 Q1 15.6 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Polo Cuadro, Cristina de Francisco, Ruth Vela González, Milagros Bermejo, Fernando Blanco, Ignacio de la Serna, Álvaro Bujanda, Luis Bernal, Lorena Rueda García, José Luis Gargallo-Puyuelo, Carla J Universidad de Zaragoza (orcid)0000-0002-3545-2707 Fuentes-Valenzuela, Esteban Castro, Beatriz Guardiola, Jordi Ladrón, Gemma Suria, Carles Sáez Fuster, Julia Gisbert, Javier P Sicilia, Beatriz Gomez, Raquel Muñoz Vilafranca, Carmen Barreiro-De Acosta, Manuel Peña, Elena Castillo Pradillo, Marta Cerrillo, Elena Calvet, Xavier Manceñido, Noemí Monfort i Miquel, David Marín, Sandra Roig, Cristina Marce, Ainhoa Ramírez de Piscina, Patricia Betoré, Elena Martin-Cardona, Albert Teller, Marta Alonso Abreu, Inmaculada Maroto, Nuria Frago, Santiago Gardeazabal, Diego Pérez-Martínez, Isabel Febles González, Ángel David Barrero, Sara Taxonera, Carlos García de la Filia, Irene Ezkurra-Altuna, Ander Madero, Lucía Martín-Arranz, María Dolores Gomollón, Fernando Universidad de Zaragoza (orcid)0000-0003-0076-3529 Domènech, Eugeni García-López, Santiago Universidad de Zaragoza (orcid)0000-0003-3970-5457 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 18, 4 (2024), 578-588 J. Crohns Colitis Journal of Crohn's & colitis 1873-9946 366975 http://zaguan.unizar.es/record/136332/files/texto_completo.pdf Versión publicada 2816875 http://zaguan.unizar.es/record/136332/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:136332 articulos driver 2026-02-17-20:33:26 ARTICLE