000144684 001__ 144684
000144684 005__ 20240906111327.0
000144684 0247_ $$2doi$$a10.1089/jmf.2023.0206
000144684 0248_ $$2sideral$$a139195
000144684 037__ $$aART-2024-139195
000144684 041__ $$aeng
000144684 100__ $$aOsés, Sandra M.
000144684 245__ $$aPhenolic composition, antiradical, antimicrobial, and anti-inflammatory activities of propolis extracts from North East Spain
000144684 260__ $$c2024
000144684 5060_ $$aAccess copy available to the general public$$fUnrestricted
000144684 5203_ $$aAntioxidant-related parameters and anti-inflammatory and antimicrobial activities against Listeria monocytogenes were assessed in eight North East Spain poplar propolis samples. Propolis extracts (PEs) were obtained using 70% ethanol (PEE) and methanol (PME). Yield and total phenol compounds were higher in PEE. Phenolic acids were analyzed by a high-performance liquid chromatograph–diode array detector. Caffeic and ferulic acids were quantified in all PEE and PME. All samples contained p-coumaric acid (quantified in 6 PEE and in 3 PME). Ascorbic acid was detected in all propolis, but mainly quantified in PME (≤0.37 mg/g PE). Biological properties were tested on PEE. As for antiradical activities, trolox equivalent antioxidant capacity (TEAC) [against 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)•+], ranged between 578 and 4620 µmol trolox/g, 2,2-diphenyl-1-picrylhydrazyl (DPPH) (against DPPH free radical), between 0.049 and 0.094 mg/mL, antioxidant activity against hydroxyl (•OH) radical (AOA), between 0.04 and 11.01 mmol uric acid/g, and oxygen radical absorbance capacity (ORAC) against peroxyl (ROO•) radical between 122 and 3282 µmol trolox/g. Results of TEAC, AOA, and ORAC were significantly correlated. IC50 anti-inflammatory activity ranged from 1.08 to 6.19 mg/mL. Propolis showed higher inhibitory activity against L. monocytogenes CECT934 and L. monocytogenes CP101 by agar well diffusion (P < .05) (10.5 and 10.2 mm, respectively) than against L. monocytogenes CP102 (7.0 mm). Data of this research show that North East Spain propolis may be of interest for pharmaceutical and food industry use.
000144684 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000144684 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000144684 700__ $$aFernández-Muiño, Miguel A.
000144684 700__ $$aRodríguez-Fernández, Andrea
000144684 700__ $$aSancho, M. Teresa
000144684 700__ $$0(orcid)0000-0002-6460-1388$$aLázaro, Regina$$uUniversidad de Zaragoza
000144684 700__ $$0(orcid)0000-0002-1668-4940$$aBayarri, Susana$$uUniversidad de Zaragoza
000144684 7102_ $$12008$$2640$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Nutrición Bromatología
000144684 773__ $$g27, 6 (2024), 563-574$$pJ. med. food$$tJOURNAL OF MEDICINAL FOOD$$x1096-620X
000144684 8564_ $$s707601$$uhttps://zaguan.unizar.es/record/144684/files/texto_completo.pdf$$yPostprint
000144684 8564_ $$s2704770$$uhttps://zaguan.unizar.es/record/144684/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000144684 909CO $$ooai:zaguan.unizar.es:144684$$particulos$$pdriver
000144684 951__ $$a2024-09-06-10:24:01
000144684 980__ $$aARTICLE