000144929 001__ 144929
000144929 005__ 20240920135617.0
000144929 0247_ $$2doi$$a10.1016/j.idairyj.2024.106058
000144929 0248_ $$2sideral$$a139784
000144929 037__ $$aART-2024-139784
000144929 041__ $$aeng
000144929 100__ $$aGraikini, D.$$uUniversidad de Zaragoza
000144929 245__ $$aComparative study on the biological activity of bovine and ovine PP3 and of their hydrolysates
000144929 260__ $$c2024
000144929 5060_ $$aAccess copy available to the general public$$fUnrestricted
000144929 5203_ $$aThis study investigated the bioactivity of bovine and ovine proteose-peptone (PPT) fractions, specifically the proteose-peptone component 3 (PP3) and its enzymatic hydrolysate. The antioxidant capacity of the above fractions and their activity against Cronobacter sakazakii and rotavirus were evaluated. Results revealed strong interspecies differences on their bioactivity. Thus, antioxidant activity of bovine PPT decreased with the fractionation but increased for ovine PPT, the latter being more active in all cases. Moreover, the antibacterial activity of hydrolyzed bovine PP3 showed high concentration-dependence reaching a maximum of 6.82 logarithmic cycle reduction at 4 mg mL−1, for 24 h of incubation. Conversely, neither intact nor hydrolyzed ovine PP3 were able to reduce the bacterial growth. Finally, both bovine and ovine PP3 neutralized rotavirus in a dose-response way, the former being more effective. Interestingly, the antiviral activity of bovine PP3 increased after hydrolysis, whereas the ovine counterpart lost almost all of its antirotaviral capacity.
000144929 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A20-23R$$9info:eu-repo/grantAgreement/EC/H2020/801586/EU/International Doctoral Programme for Talent Attraction to the Campus of International Excellence of the Ebro Valley/IberusTalent$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 801586-IberusTalent$$9info:eu-repo/grantAgreement/ES/MINECO/AGL2017-82987-R
000144929 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000144929 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000144929 700__ $$aHadidian, M.
000144929 700__ $$aAbad, I.$$uUniversidad de Zaragoza
000144929 700__ $$0(orcid)0000-0003-4505-0418$$aParrón, J. A.
000144929 700__ $$0(orcid)0000-0003-2680-7593$$aRipollés, D.
000144929 700__ $$0(orcid)0000-0003-2555-8425$$aPérez, M. D.$$uUniversidad de Zaragoza
000144929 700__ $$0(orcid)0000-0001-5373-9210$$aCalvo, M.$$uUniversidad de Zaragoza
000144929 700__ $$0(orcid)0000-0001-5964-823X$$aSánchez, L.$$uUniversidad de Zaragoza
000144929 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos
000144929 773__ $$g159 (2024), 106058 [9 pp.]$$pInt. dairy j.$$tINTERNATIONAL DAIRY JOURNAL$$x0958-6946
000144929 8564_ $$s4178689$$uhttps://zaguan.unizar.es/record/144929/files/texto_completo.pdf$$yVersión publicada
000144929 8564_ $$s2695461$$uhttps://zaguan.unizar.es/record/144929/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000144929 909CO $$ooai:zaguan.unizar.es:144929$$particulos$$pdriver
000144929 951__ $$a2024-09-20-13:00:46
000144929 980__ $$aARTICLE