144929 20260217205518.0 doi 10.1016/j.idairyj.2024.106058 sideral 139784 ART-2024-139784 eng Graikini, D. Universidad de Zaragoza Comparative study on the biological activity of bovine and ovine PP3 and of their hydrolysates 2024 Access copy available to the general public Unrestricted This study investigated the bioactivity of bovine and ovine proteose-peptone (PPT) fractions, specifically the proteose-peptone component 3 (PP3) and its enzymatic hydrolysate. The antioxidant capacity of the above fractions and their activity against Cronobacter sakazakii and rotavirus were evaluated. Results revealed strong interspecies differences on their bioactivity. Thus, antioxidant activity of bovine PPT decreased with the fractionation but increased for ovine PPT, the latter being more active in all cases. Moreover, the antibacterial activity of hydrolyzed bovine PP3 showed high concentration-dependence reaching a maximum of 6.82 logarithmic cycle reduction at 4 mg mL−1, for 24 h of incubation. Conversely, neither intact nor hydrolyzed ovine PP3 were able to reduce the bacterial growth. Finally, both bovine and ovine PP3 neutralized rotavirus in a dose-response way, the former being more effective. Interestingly, the antiviral activity of bovine PP3 increased after hydrolysis, whereas the ovine counterpart lost almost all of its antirotaviral capacity. info:eu-repo/grantAgreement/ES/DGA/A20-23R info:eu-repo/grantAgreement/EC/H2020/801586/EU/International Doctoral Programme for Talent Attraction to the Campus of International Excellence of the Ebro Valley/IberusTalent This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 801586-IberusTalent info:eu-repo/grantAgreement/ES/MINECO/AGL2017-82987-R info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 3.4 2024 FOOD SCIENCE & TECHNOLOGY 73 / 182 = 0.401 2024 Q2 T2 0.849 2024 Food Science 2024 Q1 Applied Microbiology and Biotechnology 2024 Q2 7.4 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Hadidian, M. Abad, I. Universidad de Zaragoza Parrón, J. A. (orcid)0000-0003-4505-0418 Ripollés, D. (orcid)0000-0003-2680-7593 Pérez, M. D. Universidad de Zaragoza (orcid)0000-0003-2555-8425 Calvo, M. Universidad de Zaragoza (orcid)0000-0001-5373-9210 Sánchez, L. Universidad de Zaragoza (orcid)0000-0001-5964-823X 2008 780 Universidad de Zaragoza Dpto. Produc.Animal Cienc.Ali. Área Tecnología de Alimentos 159 (2024), 106058 [9 pp.] Int. dairy j. INTERNATIONAL DAIRY JOURNAL 0958-6946 4178689 http://zaguan.unizar.es/record/144929/files/texto_completo.pdf Versión publicada 2695461 http://zaguan.unizar.es/record/144929/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:144929 articulos driver 2026-02-17-20:27:32 ARTICLE