000145082 001__ 145082
000145082 005__ 20241015105722.0
000145082 0247_ $$2doi$$a10.1177/03009858241269836
000145082 0248_ $$2sideral$$a139847
000145082 037__ $$aART-2024-139847
000145082 041__ $$aeng
000145082 100__ $$0(orcid)0000-0003-0770-9250$$aAusejo, Raquel$$uUniversidad de Zaragoza
000145082 245__ $$aTesticular tumors in commercial boars with infertility: A gross, histologic, and immunohistochemical study
000145082 260__ $$c2024
000145082 5060_ $$aAccess copy available to the general public$$fUnrestricted
000145082 5203_ $$aTumors in boars are uncommon, and testicular tumors even rarer. This study describes the pathological and immunohistochemical characteristics of a case series of testicular tumors in commercial boars with fertility problems. Tumors were detected in 19 of 333 animals (19/333, 5.9%). Macroscopically, tumors were observed in 13 (13/19, 68%) boars, while 6 cases (6/19, 32%) were only detected by microscopic examination. Testicular enlargement was observed in 1 boar, while in the others, tumors were only observed after removal of the scrotal skin or after sectioning of the testis. Histologically, tumors were classified as seminomas (16/19, 84%), mixed germ cell-stromal tumors (2/19, 11%), and B-cell lymphoma (1/19, 5%). Seminomas had 3 different growth patterns: intratubular (6/16, 38%), diffuse (4/16, 25%), and intratubular/diffuse (6/16, 38%). All tumors that were not evident on macroscopic examination were intratubular seminomas. Intratesticular metastases were observed in 2 cases and extratesticular metastases, located in the pampiniform plexus, were observed in 1 case. In 1 seminoma, the rete testis was also involved. By immunohistochemistry, all intratubular seminomas were negative for c-kit, cytokeratin, and vimentin. In diffuse seminomas, c-kit and cytokeratin were also negative, while vimentin showed granular or perinuclear cytoplasmic labeling in some areas. PAX-5 and CD-3 antibodies classified the lymphoma as a B-cell lymphoma. This study suggests that testicular tumors in boars may be more common than previously reported, especially when microscopic examination is performed. It also shows that testicular tumors in pigs are predominantly seminomas.
000145082 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000145082 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000145082 700__ $$0(orcid)0000-0001-6964-7011$$aFalceto, María Victoria$$uUniversidad de Zaragoza
000145082 700__ $$0(orcid)0000-0001-9907-2941$$aMitjana, Olga$$uUniversidad de Zaragoza
000145082 700__ $$aGarrido, Ana María$$uUniversidad de Zaragoza
000145082 700__ $$0(orcid)0000-0002-7173-7216$$aBadiola, Juan José$$uUniversidad de Zaragoza
000145082 700__ $$0(orcid)0000-0001-6629-6842$$aMoreno, Bernardino$$uUniversidad de Zaragoza
000145082 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000145082 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000145082 773__ $$pVet. pathol.$$tVeterinary Pathology$$x0300-9858
000145082 8564_ $$s2600425$$uhttps://zaguan.unizar.es/record/145082/files/texto_completo.pdf$$yPostprint
000145082 8564_ $$s2768060$$uhttps://zaguan.unizar.es/record/145082/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000145082 909CO $$ooai:zaguan.unizar.es:145082$$particulos$$pdriver
000145082 951__ $$a2024-10-15-10:56:34
000145082 980__ $$aARTICLE