145082 20260217205556.0 doi 10.1177/03009858241269836 sideral 139847 ART-2024-139847 eng Ausejo, Raquel Universidad de Zaragoza (orcid)0000-0003-0770-9250 Testicular tumors in commercial boars with infertility: A gross, histologic, and immunohistochemical study 2024 Access copy available to the general public Unrestricted Tumors in boars are uncommon, and testicular tumors even rarer. This study describes the pathological and immunohistochemical characteristics of a case series of testicular tumors in commercial boars with fertility problems. Tumors were detected in 19 of 333 animals (19/333, 5.9%). Macroscopically, tumors were observed in 13 (13/19, 68%) boars, while 6 cases (6/19, 32%) were only detected by microscopic examination. Testicular enlargement was observed in 1 boar, while in the others, tumors were only observed after removal of the scrotal skin or after sectioning of the testis. Histologically, tumors were classified as seminomas (16/19, 84%), mixed germ cell-stromal tumors (2/19, 11%), and B-cell lymphoma (1/19, 5%). Seminomas had 3 different growth patterns: intratubular (6/16, 38%), diffuse (4/16, 25%), and intratubular/diffuse (6/16, 38%). All tumors that were not evident on macroscopic examination were intratubular seminomas. Intratesticular metastases were observed in 2 cases and extratesticular metastases, located in the pampiniform plexus, were observed in 1 case. In 1 seminoma, the rete testis was also involved. By immunohistochemistry, all intratubular seminomas were negative for c-kit, cytokeratin, and vimentin. In diffuse seminomas, c-kit and cytokeratin were also negative, while vimentin showed granular or perinuclear cytoplasmic labeling in some areas. PAX-5 and CD-3 antibodies classified the lymphoma as a B-cell lymphoma. This study suggests that testicular tumors in boars may be more common than previously reported, especially when microscopic examination is performed. It also shows that testicular tumors in pigs are predominantly seminomas. info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 1.7 2024 VETERINARY SCIENCES 58 / 170 = 0.341 2024 Q2 T2 PATHOLOGY 52 / 90 = 0.578 2024 Q3 T2 0.776 2024 Veterinary (miscellaneous) 2024 Q1 5.0 2024 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Falceto, María Victoria Universidad de Zaragoza (orcid)0000-0001-6964-7011 Mitjana, Olga Universidad de Zaragoza (orcid)0000-0001-9907-2941 Garrido, Ana María Universidad de Zaragoza Badiola, Juan José Universidad de Zaragoza (orcid)0000-0002-7173-7216 Moreno, Bernardino Universidad de Zaragoza (orcid)0000-0001-6629-6842 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal 62, 1 (2024), [13 pp.] Vet. pathol. Veterinary Pathology 0300-9858 2600425 http://zaguan.unizar.es/record/145082/files/texto_completo.pdf Postprint 2768060 http://zaguan.unizar.es/record/145082/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:145082 articulos driver 2026-02-17-20:42:39 ARTICLE