doi:10.1016/j.jsams.2024.08.207engLegaz-Arrese, AlejandroSitko, SebastianCirer-Sastre, RafelMayolas-Pi, CarmenJiménez-Gaytán, Romario RivelinoOrocio, Ricardo NavarroGarcía, Ricardo LopezCorral, Pedro Gualberto MoralesReverter-Masia, JoaquínGeorge, KeithCarranza-García, Luis EnriqueThe kinetics of cardiac troponin T release during and after 1- and 6-h maximal cycling trialsART-2025-139928Objectives: In this study, the effects of short-duration high-intensity exercise and long-duration exercise on high-sensitivity cardiac troponin T (hs-cTnT) levels were compared. Methods: Twelve male amateur cyclists performed 1- and 6-h cycling trials. In both exercise trials, hs-cTnT was assessed at rest, immediately postexercise and at 1, 3, 6, 12, and 24 h postexercise. Additionally, hs-cTnT levels were assessed every hour during the 6-h trial. Results: Exercise resulted in an increase in hs-cTnT levels in all subjects. Circulating hs-cTnT levels increased in both exercise trials (p < 0.001), with higher peak values occurring after the 1-h trial compared with those of the 6-h trial (p = 0.023). The upper reference limit (URL) exceeded 83 % of the participants in the 1-h trial and 42 % of the participants in the 6-h trial. There was substantial individual variability in peak hs-cTnT in both trials. Values of hs-cTnT were greater after exercise than during exercise for the 6-h trial. For both exercise trials, the maximum postexercise hs-cTnT values correlated with the %HRMAX (r = 0.906 for the 1-h trial, r = 0.735 for the 6-h trial). For the 1-h trial, the maximum postexercise hs-cTnT values were observed at 3 h in all subjects. No significant difference in the hs-cTnT values was observed for the 6-h trial during the first 12 h postexercise. Conclusions: Our results demonstrated greater hs-cTnT levels in young male participants after a 1-h cycling trial than after a 6-h cycling trial, despite a substantially greater energy expenditure and total external work completed in the 6-h trial. Postexercise hs-cTnT values are associated with relative exercise intensity.2025http://zaguan.unizar.es/record/14509210.1016/j.jsams.2024.08.207http://zaguan.unizar.es/record/145092oai:zaguan.unizar.es:145092JOURNAL OF SCIENCE AND MEDICINE IN SPORT 28, 1 (2025), 3-8by-nc-ndhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccess