doi:10.1016/j.jorganchem.2024.123377engCored, JorgeSánchez, AntonioViguri, FernandoRodríguez, RicardoLamata, PilarCarmona, DanielEnantioselective Friedel-Crafts alkylation of 1,3,5-trimethoxybenzene with trans-ß-nitrostyrenes catalysed by [Cp*Rh{(R)-Prophos}(H2O)][SbF6]2 (Prophos = propane-1,2-diyl-bis(diphenylphosphane)ART-2024-139908The aqua complex (SRh,RC)-[Cp*Rh{(R)-Prophos}(H2O)][SbF6]2 (Prophos = propane-1,2-diyl-bis(diphenylphosphane) catalyses the asymmetric Friedel-Crafts (FC) alkylation of 1,3,5-trimethoxybenzene with trans-β-nitrostyrenes. Only the monoalkylated adduct was obtained in all cases with enantioselectivities of up to 93/7 e.r. Solution NMR measurements have allowed us to detect and characterise catalytic intermediates such as metal-trans-β-nitrostyrene and metal‑aci-nitro complexes, as well as free aci‑nitro compound. Based on these studies, a Michael-type Friedel-Crafts mechanism is proposed.2024http://zaguan.unizar.es/record/14511110.1016/j.jorganchem.2024.123377http://zaguan.unizar.es/record/145111oai:zaguan.unizar.es:145111info:eu-repo/grantAgreement/ES/DGA/E05-23Rinfo:eu-repo/grantAgreement/ES/MCIU-AEI-FEDER/PID2021-122406NB-I00info:eu-repo/grantAgreement/ES/MCIU/CTQ2018-095561-BI00Journal of Organometallic Chemistry 1021 (2024), 123377 [13 pp.]by-nchttps://creativecommons.org/licenses/by-nc/4.0/deed.esinfo:eu-repo/semantics/openAccess