145171 20260217205530.0 doi 10.1186/s13690-024-01354-w sideral 139997 ART-2024-139997 eng León-Herrera, Sandra Universidad de Zaragoza (orcid)0000-0002-1200-5904 Effectiveness of an online multimodal rehabilitation program in long COVID patients: a randomized clinical trial 2024 Access copy available to the general public Unrestricted Background Digital interventions are expected to facilitate the treatment of patients suffering from Long COVID. This trial assesses the effectiveness of a multimodal rehabilitation program —comprising both online and synchronous components— in managing the characteristic symptoms of Long COVID and, consequently, in improving quality of life. It also aims to identify which changes in measured variables from baseline (T0) to post-intervention (T1) predict an improvement in quality of life. Methods A blind randomized controlled trial was conducted with two parallel groups: (1) the control group, which received usual treatment from the primary care physician and (2) the intervention group, which received usual treatment in addition to an online multimodal rehabilitation program. The data were collected at two time points: prior to the start of the intervention and three months after it. The main outcome variable was quality of life, encompassing both mental health and physical health-related quality of life. Sociodemographic and clinical variables were collected as secondary variables. Results A total of 134 participants (age 48.97 ± 7.64; 84.33% female) were included and randomized into the control group (67 participants) and the intervention group (67 participants). Comparative analyses conducted before and after the intervention showed a significant improvement in the mental health-related quality of life of the participants who received the intervention, with a mean increase of 1.98 points (p < 0.05). Linear regression analyses revealed that both received the intervention (b = 3.193; p < 0.05) and an increased self-efficacy (b = 0.298; p < 0.05) were predictors of greater improvement in mental health-related quality of life. info:eu-repo/grantAgreement/ES/DGA/B21-23R-GAIAP info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI21-01356 info:eu-repo/grantAgreement/ES/ISCIII/PI22-01070 info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 3.2 2024 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 91 / 421 = 0.216 2024 Q1 T1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 91 / 421 = 0.216 2024 Q1 T1 1.078 2024 Public Health, Environmental and Occupational Health 2024 Q1 5.4 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Oliván-Blázquez, Bárbara Universidad de Zaragoza (orcid)0000-0001-6565-9699 Sánchez-Recio, Raquel Universidad de Zaragoza (orcid)0000-0002-0078-0663 Méndez-López, Fátima Universidad de Zaragoza (orcid)0000-0002-6409-9041 Magallón-Botaya, Rosa Universidad de Zaragoza (orcid)0000-0002-5494-6550 Sánchez-Arizcuren, Rafael Universidad de Zaragoza (orcid)0000-0001-8176-3306 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 4009 740 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Social 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 1006 413 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Fisioterapia 82, 159 (2024), [13 pp.] Arch. public health Archives of public health 0778-7367 1712696 http://zaguan.unizar.es/record/145171/files/texto_completo.pdf Versión publicada 2087573 http://zaguan.unizar.es/record/145171/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:145171 articulos driver 2026-02-17-20:32:05 ARTICLE