145345 20241024135330.0 doi 10.1016/j.neulet.2010.10.007 sideral 72888 ART-2011-72888 eng Pelaez-Coca, Mariola (orcid)0000-0002-0690-3193 Discrimination of AD and normal subjects from MRI: Anatomical versus statistical regions 2011 This work is a feature-extraction and classification study between Alzheimer's disease (AD) patients and normal subjects. Voxel-wise morphological features of brain MRI are defined as the Jacobian determinants that measure the local volume change between each subject and a given atlas. The goal of this work is to determine the region of interest (ROI) which is best suited for classification. Two types of ROIs are considered: anatomical regions, that were automatically segmented in the atlas (amygdalae, hippocampi and lateral ventricles); and statistical regions, defined from group comparison statistical maps. Classification performance was assessed with five classifiers on 20 pairs of matched training and test groups of subjects from the ADNI database. In this study the statistical masks provided the best classification performance. info:eu-repo/semantics/closedAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 2.105 2011 NEUROSCIENCES 170 / 244 = 0.697 2011 Q3 T3 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Bossa, Matias Universidad de Zaragoza (orcid)0000-0001-5127-2573 Olmos, Salvador Universidad de Zaragoza (orcid)0000-0002-1869-7227 5008 X Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Proy. investigación JBA 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 487, 1 (2011), 113-117 Neurosci. lett. NEUROSCIENCE LETTERS 0304-3940 969053 http://zaguan.unizar.es/record/145345/files/texto_completo.pdf Versión publicada 2994606 http://zaguan.unizar.es/record/145345/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:145345 articulos driver 2024-10-24-12:10:52 ARTICLE