000145416 001__ 145416
000145416 005__ 20241024135331.0
000145416 0247_ $$2doi$$a10.3390/photonics11090795
000145416 0248_ $$2sideral$$a140197
000145416 037__ $$aART-2024-140197
000145416 041__ $$aeng
000145416 100__ $$aSafarian Baloujeh, Ebrahim
000145416 245__ $$aEffect of Small Angle Misalignments on Ocular Wavefront Zernike Coefficients
000145416 260__ $$c2024
000145416 5060_ $$aAccess copy available to the general public$$fUnrestricted
000145416 5203_ $$aPurpose: To assess the possible impact of minor changes in fixation on wavefront measurements as a potential constraint in detecting subtle temporal variations in ocular wavefront error. Methods: Twelve healthy subjects with an average age of 36.3 ± 8.8 were instructed to put their heads in the aberrometer’s chin-rest and look at a fixation target that was embedded in the device. The fixation targets were readily observable to the participants without accommodation, thanks to the aberrometer’s Badal system. When each eye was staring at the target, its wavefront aberration was recorded three times and then averaged for further analysis. The averaged Zernike coefficients were rescaled to the smallest value of the maximum round pupil found among all eyes (4.41 mm), and this procedure was repeated for each target. Results: Alteration of the fixation targets caused changes to the Zernike coefficients of defocus (C(2,0)), vertical trefoil (C(3,–3)), vertical coma (C(3,–1)), horizontal coma (C(3,1)), oblique trefoil (C(3,3)), primary spherical aberration (C(4,0)), and secondary spherical aberration (C(6,0)), but the changes were not statistically significant. Nevertheless, an alteration in the target’s size and shape exhibited a significant correlation across all of the aforementioned coefficients in both eyes (p < 0.05). The total RMS of aberrations and the RMS of the spherical-like aberrations were both lowest while choosing the larger Maltese cross, and the bigger E-letter minimized the RMS of HOA and comatic aberrations. Conclusion: The aberrometric changes occur as a consequence of altering the fixational gaze and are within the range of the changes found after performing a near-vision task, so they might potentially act as a confounding factor when attempting to identify such small variations in the ocular wavefront. Using a smaller E-letter (5 arcmin) as an internal fixation target resulted in the least standard deviation of measurements, fixational stability, and higher accuracy in ocular wavefront measurements.
000145416 536__ $$9info:eu-repo/grantAgreement/EC/H2020/956720/EU/Opto-Biomechanical Eye Research Network/OBERON$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 956720-OBERON
000145416 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000145416 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000145416 700__ $$0(orcid)0000-0002-9068-7728$$aÁvila, Francisco J.$$uUniversidad de Zaragoza
000145416 700__ $$aGonzález-Méijome, José M.
000145416 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000145416 773__ $$g11, 9 (2024), 795 [10 pp.]$$pPhotonics (Basel)$$tPhotonics$$x2304-6732
000145416 8564_ $$s1674057$$uhttps://zaguan.unizar.es/record/145416/files/texto_completo.pdf$$yVersión publicada
000145416 8564_ $$s2654225$$uhttps://zaguan.unizar.es/record/145416/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000145416 909CO $$ooai:zaguan.unizar.es:145416$$particulos$$pdriver
000145416 951__ $$a2024-10-24-12:12:35
000145416 980__ $$aARTICLE