000145436 001__ 145436
000145436 005__ 20241030091919.0
000145436 0247_ $$2doi$$a10.1007/s00436-024-08369-w
000145436 0248_ $$2sideral$$a140301
000145436 037__ $$aART-2024-140301
000145436 041__ $$aeng
000145436 100__ $$0(orcid)0000-0001-5750-3643$$aPeris, María Paz$$uUniversidad de Zaragoza
000145436 245__ $$aLeishmania infantum infection in European badgers (Meles meles) from northeastern Spain: a histopathological and immunohistochemical investigation
000145436 260__ $$c2024
000145436 5060_ $$aAccess copy available to the general public$$fUnrestricted
000145436 5203_ $$aThe European badger (Meles meles) is a common mustelid species known as a significant reservoir for various human and animal diseases. Studies investigating Leishmania infection in European badgers across Mediterranean regions have yielded inconsistent findings. In Spain, results are particularly controversial: some studies confirm the presence of Leishmania in badgers, while others do not. Our study aimed to conduct a retrospective histopathological and immunohistochemical analysis to detect Leishmania in tissues of nine European badgers from northeastern Spain, a region previously unevaluated for Leishmania infection in this species. Microscopic examination revealed lesions indicative of leishmaniosis in the lymph nodes and spleens of six badgers. In one of them, Leishmania-like structures were identified in multiple organs and confirmed via immunohistochemistry. Parasites were detected in the lymph nodes, spleen, adrenal glands, and pancreas. The parasite load was high in the adrenal glands, moderate in the lymph nodes and spleen, and low in the pancreas. No parasites were found in other examined organs. This finding represents a frequency of 11.11% (1/9) of Leishmania infection among the badgers we studied. Further investigation of wildlife and atypical reservoirs can enhance our understanding of the pathogenesis of this significant zoonotic disease.
000145436 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A05-17R
000145436 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000145436 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000145436 700__ $$0(orcid)0000-0003-2208-1350$$aMartínez-Durán, David$$uUniversidad de Zaragoza
000145436 700__ $$aGarcía, Patricia
000145436 700__ $$aGonzález, Chabier
000145436 700__ $$0(orcid)0000-0001-9778-6545$$aMorales, Mariano$$uUniversidad de Zaragoza
000145436 700__ $$0(orcid)0000-0002-2048-4749$$aCastillo, Juan Antonio$$uUniversidad de Zaragoza
000145436 700__ $$0(orcid)0000-0002-7173-7216$$aBadiola, Juan José$$uUniversidad de Zaragoza
000145436 700__ $$0(orcid)0000-0001-6629-6842$$aMoreno, Bernardino$$uUniversidad de Zaragoza
000145436 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000145436 773__ $$g123, 346 (2024), [7 pp.]$$pParasitol. res.$$tParasitology Research$$x0932-0113
000145436 8564_ $$s1238502$$uhttps://zaguan.unizar.es/record/145436/files/texto_completo.pdf$$yVersión publicada
000145436 8564_ $$s2394068$$uhttps://zaguan.unizar.es/record/145436/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000145436 909CO $$ooai:zaguan.unizar.es:145436$$particulos$$pdriver
000145436 951__ $$a2024-10-30-08:48:25
000145436 980__ $$aARTICLE