000145740 001__ 145740 000145740 005__ 20241122130824.0 000145740 0247_ $$2doi$$a10.1080/01652176.2024.2421308 000145740 0248_ $$2sideral$$a140644 000145740 037__ $$aART-2024-140644 000145740 041__ $$aeng 000145740 100__ $$aMarteles, Diana$$uUniversidad de Zaragoza 000145740 245__ $$aAssessment of the exposure to Phlebotomus perniciosus and the presence of anti-Leishmania infantum antibodies in stray cats in an endemic region of Spain, and their potential correlation with environmental factors 000145740 260__ $$c2024 000145740 5060_ $$aAccess copy available to the general public$$fUnrestricted 000145740 5203_ $$aPhlebotomus perniciosus is a major vector of Leishmania infantum in the Mediterranean. While the seroprevalence of leishmaniosis in Spanish dogs and cats has been studied, data on the exposure of cats to P. perniciosus bites under natural conditions without repellents is limited. Stray cats could serve as sentinels for L. infantum and P. perniciosus exposure. This study analyzed sera from 204 apparently healthy stray cats, collected from January 2021 to January 2022, for antibodies against P. perniciosus saliva and L. infantum parasites. Anti-sand fly antibodies were detected in 40.69% of cats using an ELISA with the recombinant salivary protein SP03B of P. perniciosus. Seroprevalence of L. infantum infection was 23.52% by Western blot and 27.41% by ELISA, with an overall seroprevalence of 40.69% (95% CI 34.18–47.54%). This is the first assessment of antibody response to P. perniciosus saliva and L. infantum in naturally exposed stray cats in Spain. Further research is needed to examine the salivary antigens recognized by cats and to explore the relationship between P. perniciosus exposure and L. infantum infection severity in cats. 000145740 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/ 000145740 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000145740 700__ $$0(orcid)0000-0002-9071-1919$$aMartínez, María Victoria 000145740 700__ $$0(orcid)0000-0002-2557-4890$$aFernández, Antonio$$uUniversidad de Zaragoza 000145740 700__ $$aRiera, Cristina 000145740 700__ $$aFisa, Roser 000145740 700__ $$aRoca-Geronès, Xavier 000145740 700__ $$aChavez-Fisa, Sarah 000145740 700__ $$aCastañeda, Sergio 000145740 700__ $$aRamírez, Juan David 000145740 700__ $$aDavis, Janine Elizabeth 000145740 700__ $$aSumova, Petra 000145740 700__ $$aVolf, Petr 000145740 700__ $$0(orcid)0000-0003-2957-1379$$aVerde, Maite$$uUniversidad de Zaragoza 000145740 700__ $$0(orcid)0000-0002-8727-0323$$aGonzález, Ana$$uUniversidad de Zaragoza 000145740 700__ $$aAlcover, María Magdalena 000145740 700__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, Sergio$$uUniversidad de Zaragoza 000145740 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000145740 773__ $$g44, 1 (2024), [9 pp.]$$pVet. q.$$tVETERINARY QUARTERLY$$x0165-2176 000145740 8564_ $$s1260065$$uhttps://zaguan.unizar.es/record/145740/files/texto_completo.pdf$$yVersión publicada 000145740 8564_ $$s1591833$$uhttps://zaguan.unizar.es/record/145740/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000145740 909CO $$ooai:zaguan.unizar.es:145740$$particulos$$pdriver 000145740 951__ $$a2024-11-22-11:53:37 000145740 980__ $$aARTICLE