146986 20241205091043.0 doi 10.3390/children9050585 sideral 129166 ART-2022-129166 eng Córdoba-Rodríguez, Diana Paola Early Life Factors Associated with Lean Body Mass in Spanish Children: CALINA Study 2022 Early life is critical for the programming of body composition. The literature links perinatal factors with fat mass development and its future effects (e.g., obesity); however, little evidence exists between early life factors and lean body mass (LBM). This study follows up on a cohort of 416 Spanish children at ages six to eight, previously evaluated at birth in the CALINA study. Here, we studied the association between early life factors, LBM, and limb strength. Parental origin/nutritional status, maternal smoking during pregnancy, gestational diabetes/weight gain/age, birth weight (BW), early feeding, and rapid weight gain (RWG) were collected from primary care records. Bioimpedance analysis, dual-energy X-ray absorptiometry, peripheral quantitative computed tomography, and a handgrip/standing long jump test were used to assess fat-free mass index (FFMI), total lean soft tissue mass index (TLSTMI), muscle cross-sectional area index (MCSAI), and limb strength, respectively. In girls, maternal smoking, gestational age, and BW were positively associated with FFM/LSTM. In boys, the parents’ BMI, BW, and RWG were positively associated with FFM/LSTM. BW was associated with handgrip strength in both. Maternal BMI in girls and RWG in boys were negatively associated with the standing long jump. Early life programming plays a key role in determining LBM in children. © MDPI. All rights reserved. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI08-0559 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI13-02359 info:eu-repo/grantAgreement/ES/ISCIII-RICORDS/RD21-0012-0012 info:eu-repo/grantAgreement/ES/RETICS-ISCIII-ERDF/RD16-0022-0013 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.4 2022 PEDIATRICS 58 / 130 = 0.446 2022 Q2 T2 0.504 2022 Pediatrics, Perinatology and Child Health 2022 Q2 2.0 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Iglesia, Iris (orcid)0000-0002-2219-3646 Gómez-Bruton, Alejandro Universidad de Zaragoza (orcid)0000-0002-0520-1640 Álvarez Sauras, María Luisa Miguel-Berges, María L. (orcid)0000-0002-2411-9538 Flores-Barrantes, Paloma Universidad de Zaragoza (orcid)0000-0002-2135-900X Casajús, José Antonio Universidad de Zaragoza (orcid)0000-0002-7215-6931 Moreno, Luis A. Universidad de Zaragoza (orcid)0000-0003-0454-653X Rodríguez, Gerardo Universidad de Zaragoza (orcid)0000-0002-7985-9912 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 1006 245 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Educación Física y Depor. 1011 670 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Pediatría 9, 5 (2022), 585 [17 pp.] Children (Basel) Children 2227-9067 1732699 http://zaguan.unizar.es/record/146986/files/texto_completo.pdf Versión publicada 2652597 http://zaguan.unizar.es/record/146986/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:146986 articulos driver 2024-12-05-08:46:07 ARTICLE