000147062 001__ 147062
000147062 005__ 20250923084445.0
000147062 0247_ $$2doi$$a10.1016/j.nut.2024.112603
000147062 0248_ $$2sideral$$a140744
000147062 037__ $$aART-2024-140744
000147062 041__ $$aeng
000147062 100__ $$ade Cuevillas, Begoña
000147062 245__ $$aParent–child microbiota relationships involved in childhood obesity: A CORALS ancillary study
000147062 260__ $$c2024
000147062 5060_ $$aAccess copy available to the general public$$fUnrestricted
000147062 5203_ $$aObjectives
Childhood obesity continues to rise worldwide. Family gut microorganisms may be associated with childhood obesity. The aim of the study was to analyze bacterial similarities in fecal microbiota composition between parent–offspring pairs as linked to body weight.
Methods
A total of 146 father/mother and offspring pairs were categorized into four groups according to the weight status of the parent–child pair as follows: group 1, parent and child with normal weight; group 2, parent and child with overweight/obesity; group 3, parent with normal weight and child with overweight/obesity; group 4, parent with overweight/obesity and child with normal weight. Anthropometric measurements and lifestyle assessments were performed in all participants. Microbiota characteristics were determined by 16S ribosomal RNA gene sequencing. Logistic regression models were performed to determine whether the abundance of any bacteria was able to predict childhood obesity. Moreover, receiver operating characteristic curves were fitted to define the relative diagnostic strength of bacterial taxa for the correct identification of childhood obesity.
Results
The absence/abundance of Catenibacterium mitsuokai, Prevotella stercorea, Desulfovibrio piger, Massiliprevotella massiliensis, and Phascolarctobacterium succinatutens was involved in body weight family associations. A positive relationship between P. succinatutens richness from parents and M. massiliensis from children was observed with regard to body weight status (odds ratio, 1.14, P = 0.013).
Conclusions
This study describes five potential gut bacteria that may be putatively involved in family weight status relationships and appear to be useful for predicting obesity.
000147062 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000147062 590__ $$a3.0$$b2024
000147062 592__ $$a0.961$$b2024
000147062 591__ $$aNUTRITION & DIETETICS$$b54 / 112 = 0.482$$c2024$$dQ2$$eT2
000147062 593__ $$aNutrition and Dietetics$$c2024$$dQ2
000147062 593__ $$aEndocrinology, Diabetes and Metabolism$$c2024$$dQ2
000147062 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000147062 700__ $$aRiezu-Boj, Jose I.
000147062 700__ $$aMilagro, Fermín I.
000147062 700__ $$aGalera Alquegui, Sergio
000147062 700__ $$aBabio, Nancy
000147062 700__ $$aPastor-Villaescusa, Belén
000147062 700__ $$aGil-Campos, Mercedes
000147062 700__ $$aLeis, Rosaura
000147062 700__ $$0(orcid)0000-0001-6173-5850$$aDe Miguel-Etayo, Pilar$$uUniversidad de Zaragoza
000147062 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis A.$$uUniversidad de Zaragoza
000147062 700__ $$aSalas-Salvadó, Jordi
000147062 700__ $$aMartínez, J. Alfredo
000147062 700__ $$aNavas-Carretero, Santiago
000147062 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000147062 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000147062 773__ $$g130 (2024), 112603 [9 pp.]$$pNutrition$$tNUTRITION$$x0899-9007
000147062 8564_ $$s923568$$uhttps://zaguan.unizar.es/record/147062/files/texto_completo.pdf$$yVersión publicada
000147062 8564_ $$s2405973$$uhttps://zaguan.unizar.es/record/147062/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000147062 909CO $$ooai:zaguan.unizar.es:147062$$particulos$$pdriver
000147062 951__ $$a2025-09-22-14:53:50
000147062 980__ $$aARTICLE