147127 20241216113259.0 doi 10.1017/S0007114512001511 sideral 77350 ART-2012-77350 eng Rodríguez, G. Universidad de Zaragoza (orcid)0000-0002-7985-9912 Effect of n-3 long chain polyunsaturated fatty acids during the perinatal period on later body composition 2012 Access copy available to the general public Unrestricted A systematic review to identify studies reporting the effects of n-3 long chain polyunsaturated fatty acids (LCPUFA) intake, during pregnancy and postnatally, on infants and young children's body composition was performed. A structured search strategy was performed in the MEDLINE (PubMed), EMBASE, and LILACS databases. Inclusion and exclusion criteria were defined according to the research question. Only those studies addressing the relationship between n-3 LCPUFA exposure during the perinatal period and later adiposity measured in terms of weight, height, body mass index (BMI), skinfold thickness and/or circumferences were included regardless of the study design. Studies quality was scored and were thereafter categorised into those reporting on maternal intake of n-3 LCPUFA during pregnancy or lactation (6 publications) or on infant's n-3 LCPUFA intake (7 publications). Two studies showed inverse associations between maternal n-3 LCPUFA intake and children's later body composition (lower adiposity, BMI or body weight), two showed direct associations and no effects were observed in the remaining two studies. Among those studies focusing on n-3 LCPUFA intake through enriched infant formulas; three observed no effect on later body composition and two showed higher weight and adiposity with increased amounts of n-3 LCPUFA. Reversely, in two studies weight and fat mass decreased. In conclusion, reported body composition differences in infants and young children were not clearly explained by perinatal n-3 LCPUFA intake via supplemented formulas, breastfeeding or maternal intakes of n-3 LCPUFA during pregnancy and lactation. Associated operational mechanisms including n-3 LCPUFA doses and sources applied are not sufficiently explained and therefore no conclusions could be made. info:eu-repo/grantAgreement/ES/Spanish Ministry of Health/RD08-0072 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 3.302 2012 NUTRITION & DIETETICS 18 / 75 = 0.24 2012 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Iglesia, I. Universidad de Zaragoza (orcid)0000-0002-2219-3646 Bel-Serrat, S. Universidad de Zaragoza Moreno, L. A. Universidad de Zaragoza (orcid)0000-0003-0454-653X 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 1006 X Universidad de Zaragoza Dpto. Fisiatría y Enfermería Proy. investigación DZA 1010 670 Universidad de Zaragoza Dpto. Pediatría Radiol.Med.Fís Área Pediatría 107, S2 (2012), S117-S128 Br. J. Nutr. British journal of nutrition 0007-1145 238699 http://zaguan.unizar.es/record/147127/files/texto_completo.pdf Postprint 1129626 http://zaguan.unizar.es/record/147127/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:147127 articulos driver 2024-12-16-11:31:52 ARTICLE