000147737 001__ 147737 000147737 005__ 20250923084439.0 000147737 0247_ $$2doi$$a10.3389/fpsyg.2024.1436611 000147737 0248_ $$2sideral$$a141198 000147737 037__ $$aART-2024-141198 000147737 041__ $$aeng 000147737 100__ $$aIbáñez, Delia 000147737 245__ $$aPre- and post-COVID 19 outbreak relationship between physical activity and depressive symptoms in Spanish adults with major depressive disorder: a secondary analysis of the RADAR-MDD cohort study 000147737 260__ $$c2024 000147737 5060_ $$aAccess copy available to the general public$$fUnrestricted 000147737 5203_ $$aAimTo evaluate the longitudinal association of sedentary behavior, light and moderate-to-vigorous physical activity (MVPA) participation with depressive symptoms and whether their possible association changed depending on the pandemic phase.MethodsThis longitudinal study conducted secondary analysis from the Spanish cohort of the Remote Assessment of Disease and Relapse – Major Depressive Disorder (RADAR-MDD) study. Depressive symptoms were assessed by the Patient Health Questionnaire (PHQ-8). Sedentary behavior and physical activity were estimated via wrist-worn devices. Linear mixed models evaluated the longitudinal associations of sedentary behavior and physical activity (light and moderate-to-vigorous intensities) with depressive symptoms.ResultsIn total, 95 participants (67.5% women, 53.0 [±10.5] years of age on average) were monitored pre-COVID-19 and included in the analyses. Pre-COVID-19, 73.7% of participants presented depression, and, on average, participated in 13.2 (±1.08) hours/day of sedentary behavior, 2.42 (±0.90) hours/day of light physical activity and 23.6 (±19.80) minutes/day of MVPA. Considering all the observations (from November 2019 to October 2020), an additional hour/day of sedentary behavior was longitudinally associated with higher depressive symptoms [βstd = 0.06, 95% confidence interval (CI) 0.10 to 0.47], whereas an additional hour/day in light physical activity was associated with lower depressive symptoms (βstd = −0.06, 95% CI −0.59 to −0.15). Time in MVPA was not associated with depressive symptomatology. The association of sedentary behavior and light physical activity with depressive symptoms was significant only during pre-COVID-19 and COVID-19 relaxation periods, whereas during the strictest periods of the pandemic with regards to the restrictions (lockdown and de-escalation), the association was not observed.ConclusionSedentary behavior and light physical activity were longitudinally associated with depressive symptoms in participants with a history of MDD. The incorporation of light physical activity should be stimulated in adults with a history of MDD. Neither sedentary behavior nor light physical activity were associated with depressive symptoms during the most restrictive COVID-19 phases, whereas sedentary behavior (positively) and light physical activity (negatively) were associated with depressive symptoms in persons with MDD before and after the COVID-19 pandemic. 000147737 536__ $$9info:eu-repo/grantAgreement/EC/H2020/115902/EU/Remote Assessment of Disease and Relapse in Central Nervous System Disorders/RADAR-CNS$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 115902-RADAR-CNS 000147737 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000147737 590__ $$a2.9$$b2024 000147737 592__ $$a0.872$$b2024 000147737 591__ $$aPSYCHOLOGY, MULTIDISCIPLINARY$$b45 / 221 = 0.204$$c2024$$dQ1$$eT1 000147737 593__ $$aPsychology (miscellaneous)$$c2024$$dQ2 000147737 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000147737 700__ $$aCondominas, Elena 000147737 700__ $$aHaro, Josep Maria 000147737 700__ $$aVázquez, Iago Giné 000147737 700__ $$aRADAR-MDD-Spain 000147737 700__ $$0(orcid)0000-0003-1272-0550$$aBailón, Raquel$$uUniversidad de Zaragoza 000147737 700__ $$aGarcia, Esther 000147737 700__ $$aKontaxis, Spyridon 000147737 700__ $$aPeñarrubia-Maria, Maria Teresa 000147737 700__ $$aArranz, Belen 000147737 700__ $$aLlaosa-Scholten, Raúl 000147737 700__ $$aGardeñes, Lluisa 000147737 700__ $$aHotopf, Matthew 000147737 700__ $$aMatcham, Faith 000147737 700__ $$aLamers, Femke 000147737 700__ $$aPenninx, Brenda W. J. H. 000147737 700__ $$aAnnas, Peter 000147737 700__ $$aFolarin, Amos 000147737 700__ $$aNarayan, Vaibhav 000147737 700__ $$aAntunes Lima, Rodrigo 000147737 700__ $$aSiddi, Sara 000147737 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac. 000147737 773__ $$g15 (2024), [12 pp.]$$pFront. psychol.$$tFrontiers in Psychology$$x1664-1078 000147737 8564_ $$s513194$$uhttps://zaguan.unizar.es/record/147737/files/texto_completo.pdf$$yVersión publicada 000147737 8564_ $$s2399787$$uhttps://zaguan.unizar.es/record/147737/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000147737 909CO $$ooai:zaguan.unizar.es:147737$$particulos$$pdriver 000147737 951__ $$a2025-09-22-14:49:08 000147737 980__ $$aARTICLE