doi:10.3390/ani14243682engAlférez, María DoloresCorda, Andreade Blas, IgnacioGago, LucasFernandes, TelmoRodríguez-Piza, IgnacioBalañá, BeatrizPentcheva, PlamenaCaruncho, JavierBarbero-Fernández, AliciaLlinás, JorgeRivas, DavidEscudero, AmaiaGómez-Ochoa, PabloComputed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in DogsART-2024-141421Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.2024http://zaguan.unizar.es/record/14794310.3390/ani14243682http://zaguan.unizar.es/record/147943oai:zaguan.unizar.es:147943Animals 14, 24 (2024), 3682 [14 pp.]byhttps://creativecommons.org/licenses/by/4.0/deed.esinfo:eu-repo/semantics/openAccess