000148085 001__ 148085
000148085 005__ 20250127144949.0
000148085 0248_ $$2sideral$$a63782
000148085 037__ $$aART-2009-63782
000148085 041__ $$aeng
000148085 100__ $$0(orcid)0000-0002-0759-9170$$aAznar, M.$$uUniversidad de Zaragoza
000148085 245__ $$aQuantitative Determination of 22 Primary Aromatic Amines by Cation-Exchange Solid-Phase Extraction and Liquid Chromatography-Mass Spectrometry
000148085 260__ $$c2009
000148085 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148085 5203_ $$aPrimary aromatic amines (PAAs) have been broadly studied due to their high toxicity. In this work a method for the analysis of 22 PAAs in aqueous simulants has been developed. The method is based on a solid-phase extraction step using cation-exchange cartridges and the subsequent analysis of the extracts by ultra-high-performance liquid chromatography with mass spectrometric detection. The recoveries obtained for all the amines analyzed ranged between 81 and 109%, linear range was between 0.03 and 75 μg L−1, with the RSD values between 4.5 and 13.4% and an average value of 7.5% and limits of detection at μg L−1 level. The method has been applied to two real samples obtained from migration experiments of polyurethane based laminates to simulant B (water with 3% (w/v) acetic acid) which represents the worst case for the migration of aromatic amines. The main amines found in both samples were methylenedianiline isomers, obtained from the corresponding residual diisocyanates used during polyurethane adhesive polymerization. The total amine concentration found was 26 and 6.3 μg of aniline equivalents per kg of food simulant.
000148085 536__ $$9info:eu-repo/grantAgreement/ES/MEC/PET2006_0512_00
000148085 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000148085 590__ $$a4.101$$b2009
000148085 591__ $$aCHEMISTRY, ANALYTICAL$$b4 / 70 = 0.057$$c2009$$dQ1$$eT1
000148085 591__ $$aBIOCHEMICAL RESEARCH METHODS$$b13 / 67 = 0.194$$c2009$$dQ1$$eT1
000148085 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000148085 700__ $$0(orcid)0000-0003-2638-9221$$aCanellas, E.$$uUniversidad de Zaragoza
000148085 700__ $$0(orcid)0000-0003-2685-5739$$aNerin, C.$$uUniversidad de Zaragoza
000148085 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000148085 7102_ $$12009$$2X$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cProy. investigación HVA
000148085 773__ $$g1216, 27 (2009), 5176-5181$$pJ. chromatogr. A$$tJournal of Chromatography A$$x0021-9673
000148085 8564_ $$s248583$$uhttps://zaguan.unizar.es/record/148085/files/texto_completo.pdf$$yPostprint
000148085 8564_ $$s1356435$$uhttps://zaguan.unizar.es/record/148085/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000148085 909CO $$ooai:zaguan.unizar.es:148085$$particulos$$pdriver
000148085 951__ $$a2025-01-27-14:45:28
000148085 980__ $$aARTICLE