000148091 001__ 148091
000148091 005__ 20250114155432.0
000148091 0247_ $$2doi$$a10.1111/add.15012
000148091 0248_ $$2sideral$$a118495
000148091 037__ $$aART-2020-118495
000148091 041__ $$aeng
000148091 100__ $$0(orcid)0000-0003-0604-5042$$aMoreno-Franco, Belén$$uUniversidad de Zaragoza
000148091 245__ $$aAssociation between alcohol consumption and subclinical femoral atherosclerosis in smoking and non-smoking men: The AWHS Study
000148091 260__ $$c2020
000148091 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148091 5203_ $$aBackground and Aims: Many addictive substances, such as tobacco and alcohol, influence atherosclerosis development. Whether or not tobacco's pro-atherosclerotic effect is influenced by alcohol consumption is unknown. We aimed to estimate the impact of alcohol intake on the presence of subclinical atherosclerosis in femoral arteries in smoking and non-smoking middle-aged men.Design, Setting and Participants: Cross-sectional analysis of a subset of the Aragon Workers Health Study (AWHS), comprising 2099 men with mean age 50.9 years without previous cardiovascular disease. Measurements: The presence of plaques in femoral arteries was assessed by high-resolution sonography. Self-reported alcohol consumption over the previous year was measured with a food frequency questionnaire. The sample was divided into four groups according to their daily grams of alcohol consumption = 1 (abstainers), = 2 to < 30, = 30 to < 60 and = 60 g/day. Participants were divided on ever-smoking (current and former) versus never-smoking strata in the main analysis. Findings: We did not find a significant association between the different levels of alcohol intake and the likelihood of developing femoral artery atherosclerosis in never-smokers. Ever-smoking was positively associated with femoral atherosclerosis overall [odds ratio (OR) = 3.00; 95% confidence interval (CI) = 2.40, 3.74; P < 0.001] and within each level of alcohol consumption. Atherosclerosis was lower in ever-smokers who consumed 2 g/day or more but less than 30 g/day with respect to those ever-smokers who were abstainers (OR = 0.70; 95% CI = 0.49, 0.99; P < 0.05). However, among these ever-smokers, atherosclerosis prevalence was still higher than among never-smokers who consumed alcohol in the same amount (2 g/day or more but less than 30 g/day) (OR = 2.73; 95% CI = 2.07, 3.61; P < 0.001). Conclusions: Among middle-aged men, moderate alcohol consumption appears to be associated with lower prevalence of femoral artery subclinical atherosclerosis compared with alcohol abstinence only in ever-smokers.
000148091 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI17-10704$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI18-01929
000148091 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000148091 590__ $$a6.526$$b2020
000148091 591__ $$aPSYCHIATRY$$b21 / 155 = 0.135$$c2020$$dQ1$$eT1
000148091 591__ $$aSUBSTANCE ABUSE$$b3 / 37 = 0.081$$c2020$$dQ1$$eT1
000148091 591__ $$aPSYCHIATRY$$b14 / 142 = 0.099$$c2020$$dQ1$$eT1
000148091 591__ $$aSUBSTANCE ABUSE$$b2 / 21 = 0.095$$c2020$$dQ1$$eT1
000148091 592__ $$a2.423$$b2020
000148091 593__ $$aPsychiatry and Mental Health$$c2020$$dQ1
000148091 593__ $$aMedicine (miscellaneous)$$c2020$$dQ1
000148091 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000148091 700__ $$aPérez-Esteban, Alejandro
000148091 700__ $$0(orcid)0000-0001-7043-0952$$aCiveira, Fernando$$uUniversidad de Zaragoza
000148091 700__ $$aGuallar-Castillón, Pilar
000148091 700__ $$0(orcid)0000-0002-9887-2629$$aCasasnovas, José Antonio$$uUniversidad de Zaragoza
000148091 700__ $$0(orcid)0000-0001-6650-8294$$aMateo-Gállego, Rocío$$uUniversidad de Zaragoza
000148091 700__ $$0(orcid)0000-0001-9142-0737$$aJarauta, Estíbaliz$$uUniversidad de Zaragoza
000148091 700__ $$0(orcid)0000-0002-7194-8275$$aMalo, Sara$$uUniversidad de Zaragoza
000148091 700__ $$0(orcid)0000-0003-3963-0846$$aLaclaustra, Martín$$uUniversidad de Zaragoza
000148091 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000148091 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000148091 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000148091 773__ $$g115, 9 (2020), 1754-1761$$pAddiction$$tADDICTION$$x0965-2140
000148091 8564_ $$s1062466$$uhttps://zaguan.unizar.es/record/148091/files/texto_completo.pdf$$yPostprint
000148091 8564_ $$s997861$$uhttps://zaguan.unizar.es/record/148091/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000148091 909CO $$ooai:zaguan.unizar.es:148091$$particulos$$pdriver
000148091 951__ $$a2025-01-13-14:27:34
000148091 980__ $$aARTICLE