000148093 001__ 148093
000148093 005__ 20250114155432.0
000148093 0247_ $$2doi$$a10.1007/s40279-020-01361-1
000148093 0248_ $$2sideral$$a120606
000148093 037__ $$aART-2021-120606
000148093 041__ $$aeng
000148093 100__ $$0(orcid)0000-0001-6523-5511$$aNavarrete Villanueva, David$$uUniversidad de Zaragoza
000148093 245__ $$aFrailty and physical fitness in elderly people: a systematic review and meta-analysis
000148093 260__ $$c2021
000148093 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148093 5203_ $$aBackground: Frailty is an age-related condition that implies a vulnerability status affecting quality of life and independence of the elderly. Physical fitness is closely related to frailty, as some of its components are used for the detection of this condition. Objectives: This systematic review and meta-analysis was conducted to investigate the magnitude of the associations between frailty and different physical fitness components and to analyse if several health-related factors can act as mediators in the relationship between physical fitness and frailty. 
Methods: A systematic search was conducted of PubMed, SPORTDiscus, and Web of Science, covering the period from the respective start date of each database to March 2020, published in English, Spanish or Portuguese. Two investigators evaluated 1649 studies against the inclusion criteria (cohort and cross-sectional studies in humans aged ≥ 60 years that measured physical fitness with validated tests and frailty according to the Fried Frailty Phenotype or the Rockwood Frailty Index). The quality assessment tool for observational cross-sectional studies was used to assess the quality of the studies. 
Results: Twenty studies including 13,527 participants met the inclusion criteria. A significant relationship was found between frailty and each physical fitness component. Usual walking speed was the physical fitness variable most strongly associated with frailty status, followed by aerobic capacity, maximum walking speed, lower body strength and grip strength. Potential mediators such as age, sex, body mass index or institutionalization status did not account for the heterogeneity between studies following a meta-regression. 
Conclusions: Taken together, these findings suggest a clear association between physical fitness components and frailty syndrome in elderly people, with usual walking speed being the most strongly associated fitness test. These results may help to design useful strategies, to attenuate or prevent frailty in elders. 
Systematic Review Registration: PROSPERO registration no. CRD42020149604 (date of registration: 03/12/2019)
000148093 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000148093 590__ $$a11.928$$b2021
000148093 591__ $$aSPORT SCIENCES$$b3 / 88 = 0.034$$c2021$$dQ1$$eT1
000148093 592__ $$a3.806$$b2021
000148093 593__ $$aMedicine (miscellaneous)$$c2021$$dQ1
000148093 593__ $$aSports Science$$c2021$$dQ1
000148093 593__ $$aOrthopedics and Sports Medicine$$c2021$$dQ1
000148093 594__ $$a19.8$$b2021
000148093 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000148093 700__ $$0(orcid)0000-0001-6492-2512$$aGómez Cabello, Alba
000148093 700__ $$aMarín Puyalto, Jorge
000148093 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, Luis Alberto$$uUniversidad de Zaragoza
000148093 700__ $$0(orcid)0000-0002-4303-4097$$aVicente Rodríguez, Germán$$uUniversidad de Zaragoza
000148093 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, José Antonio$$uUniversidad de Zaragoza
000148093 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000148093 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000148093 773__ $$g51 (2021), 143-160$$pSports med.$$tSPORTS MEDICINE$$x0112-1642
000148093 8564_ $$s892117$$uhttps://zaguan.unizar.es/record/148093/files/texto_completo.pdf$$yPostprint
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000148093 951__ $$a2025-01-13-14:27:36
000148093 980__ $$aARTICLE