000148111 001__ 148111 000148111 005__ 20250114155432.0 000148111 0247_ $$2doi$$a10.1021/acsbiomaterials.3c00859 000148111 0248_ $$2sideral$$a137559 000148111 037__ $$aART-2024-137559 000148111 041__ $$aeng 000148111 100__ $$aLomba, Laura 000148111 245__ $$aAdvances in Cryopreservatives: Exploring Safer Alternatives 000148111 260__ $$c2024 000148111 5203_ $$aCryopreservation of cells, tissues, and organs is widely used in the biomedical and research world. There are different cryopreservatives that are used for this process; however, many of them, such as DMSO, are used despite the problems they present, mainly due to the toxicity it presents to certain types of samples. The aim of this Review is to highlight the different types of substances used in the cryopreservation process. It has been shown that some of these substances are well-known, as in the case of the families of alcohols, sugars, sulfoxides, etc. However, in recent years, other compounds have appeared, such as ionic liquids, deep eutectic solvents, or certain polymers, which open the door to new cryopreservation methods and are also less toxic to frozen samples. 000148111 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000148111 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000148111 700__ $$aGarcía, Cristina B. 000148111 700__ $$aBenito, Lucía 000148111 700__ $$aSangüesa, Estela 000148111 700__ $$0(orcid)0000-0002-1275-2600$$aSantander, Sonia$$uUniversidad de Zaragoza 000148111 700__ $$aZuriaga, Estefanía 000148111 7102_ $$11012$$2315$$aUniversidad de Zaragoza$$bDpto. Farmac.Fisiol.y Med.L.F.$$cÁrea Farmacología 000148111 773__ $$g10, 1 (2024), 178-190$$pACS biomater. sci. eng.$$tACS BIOMATERIALS SCIENCE & ENGINEERING$$x2373-9878 000148111 8564_ $$s2146781$$uhttps://zaguan.unizar.es/record/148111/files/texto_completo.pdf$$yVersión publicada 000148111 8564_ $$s2259543$$uhttps://zaguan.unizar.es/record/148111/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000148111 909CO $$ooai:zaguan.unizar.es:148111$$particulos$$pdriver 000148111 951__ $$a2025-01-13-14:28:00 000148111 980__ $$aARTICLE