000148267 001__ 148267
000148267 005__ 20250115160155.0
000148267 0247_ $$2doi$$a10.1093/gerona/glz140
000148267 0248_ $$2sideral$$a118330
000148267 037__ $$aART-2020-118330
000148267 041__ $$aeng
000148267 100__ $$aSandoval-Insausti, H.
000148267 245__ $$aUltra-processed Food Consumption and Incident Frailty: A Prospective Cohort Study of Older Adults
000148267 260__ $$c2020
000148267 5203_ $$aBACKGROUND: Ultra-processed food intake has been associated with chronic conditions and mortality. The aim of this study was to assess the relationship between ultra-processed food intake and incident frailty in community-dwelling older adults. METHODS: Prospective cohort study with 1, 822 individuals aged at least 60 years who were recruited during 2008-2010 in Spain. At baseline, food consumption was obtained using a validated computerized face-to-face dietary history. Ultra-processed foods were identified according to the nature and extent of their industrial processing (NOVA classification). In 2012, incident frailty was ascertained based on Fried's criteria. Statistical analyses were performed with logistic regression and adjusted for the main potential confounders.
RESULTS: After a mean follow-up of 3.5 years, 132 cases of frailty were identified. The fully adjusted risks of frailty across increasing quartiles of the percentage of total energy intake from ultra-processed foods were the following: 0.04 (0.02-0.05), 0.05 (0.03-0.07), 0.09 (0.07-0.12), and 0.11 (0.08-0.14). Results were similar when food consumption was expressed as gram per day/body weight. Regarding ultra-processed food groups, the highest versus the lowest tertiles of consumption of yogurts and fermented milks, cakes and pastries, as well as nonalcoholic beverages (instant coffee and cocoa, packaged juices, and other nonalcoholic drinks, excluding soft drinks) were also significantly related to incident frailty. CONCLUSIONS: Consumption of ultra-processed foods is strongly associated with frailty risk in older adults. Substituting unprocessed or minimally processed foods for ultra-processed foods would play an important role in the prevention of age-related frailty. TRIAL REGISTRATION: NCT02804672.
000148267 536__ $$9info:eu-repo/grantAgreement/EC/H2020/635316/EU/Ageing Trajectories of Health: Longitudinal Opportunities and Synergies/ATHLOS$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 635316-ATHLOS$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-00609$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-01460$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-01512$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI17-1709$$9info:eu-repo/grantAgreement/ES/ISCIII/PCIN-2016-145 SALAMANDER
000148267 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000148267 590__ $$a6.053$$b2020
000148267 591__ $$aGERONTOLOGY$$b1 / 36 = 0.028$$c2020$$dQ1$$eT1
000148267 591__ $$aGERIATRICS & GERONTOLOGY$$b8 / 53 = 0.151$$c2020$$dQ1$$eT1
000148267 592__ $$a2.133$$b2020
000148267 593__ $$aGeriatrics and Gerontology$$c2020$$dQ1
000148267 593__ $$aAging$$c2020$$dQ1
000148267 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000148267 700__ $$aBlanco-Rojo, R.
000148267 700__ $$aGraciani, A.
000148267 700__ $$aLópez-García, E.
000148267 700__ $$0(orcid)0000-0003-0604-5042$$aMoreno-Franco, B.$$uUniversidad de Zaragoza
000148267 700__ $$0(orcid)0000-0003-3963-0846$$aLaclaustra, M.$$uUniversidad de Zaragoza
000148267 700__ $$aDonat-Vargas, C.
000148267 700__ $$aOrdovás, J.M.
000148267 700__ $$aRodríguez-Artalejo, F.
000148267 700__ $$aGuallar-Castillón, P.
000148267 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000148267 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000148267 773__ $$g75, 6 (2020), 1126-1133$$pJ. gerontol., Ser. A, biol. sci. med. sci.$$tThe journals of gerontology. Series A, Biological sciences and medical sciences$$x1079-5006
000148267 8564_ $$s326442$$uhttps://zaguan.unizar.es/record/148267/files/texto_completo.pdf$$yVersión publicada
000148267 8564_ $$s2422233$$uhttps://zaguan.unizar.es/record/148267/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000148267 909CO $$ooai:zaguan.unizar.es:148267$$particulos$$pdriver
000148267 951__ $$a2025-01-15-15:06:05
000148267 980__ $$aARTICLE