148267 20250115160155.0 doi 10.1093/gerona/glz140 sideral 118330 ART-2020-118330 eng Sandoval-Insausti, H. Ultra-processed Food Consumption and Incident Frailty: A Prospective Cohort Study of Older Adults 2020 BACKGROUND: Ultra-processed food intake has been associated with chronic conditions and mortality. The aim of this study was to assess the relationship between ultra-processed food intake and incident frailty in community-dwelling older adults. METHODS: Prospective cohort study with 1, 822 individuals aged at least 60 years who were recruited during 2008-2010 in Spain. At baseline, food consumption was obtained using a validated computerized face-to-face dietary history. Ultra-processed foods were identified according to the nature and extent of their industrial processing (NOVA classification). In 2012, incident frailty was ascertained based on Fried's criteria. Statistical analyses were performed with logistic regression and adjusted for the main potential confounders. RESULTS: After a mean follow-up of 3.5 years, 132 cases of frailty were identified. The fully adjusted risks of frailty across increasing quartiles of the percentage of total energy intake from ultra-processed foods were the following: 0.04 (0.02-0.05), 0.05 (0.03-0.07), 0.09 (0.07-0.12), and 0.11 (0.08-0.14). Results were similar when food consumption was expressed as gram per day/body weight. Regarding ultra-processed food groups, the highest versus the lowest tertiles of consumption of yogurts and fermented milks, cakes and pastries, as well as nonalcoholic beverages (instant coffee and cocoa, packaged juices, and other nonalcoholic drinks, excluding soft drinks) were also significantly related to incident frailty. CONCLUSIONS: Consumption of ultra-processed foods is strongly associated with frailty risk in older adults. Substituting unprocessed or minimally processed foods for ultra-processed foods would play an important role in the prevention of age-related frailty. TRIAL REGISTRATION: NCT02804672. info:eu-repo/grantAgreement/EC/H2020/635316/EU/Ageing Trajectories of Health: Longitudinal Opportunities and Synergies/ATHLOS This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 635316-ATHLOS info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-00609 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-01460 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI16-01512 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI17-1709 info:eu-repo/grantAgreement/ES/ISCIII/PCIN-2016-145 SALAMANDER info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 6.053 2020 GERONTOLOGY 1 / 36 = 0.028 2020 Q1 T1 GERIATRICS & GERONTOLOGY 8 / 53 = 0.151 2020 Q1 T1 2.133 2020 Geriatrics and Gerontology 2020 Q1 Aging 2020 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Blanco-Rojo, R. Graciani, A. López-García, E. Moreno-Franco, B. Universidad de Zaragoza (orcid)0000-0003-0604-5042 Laclaustra, M. Universidad de Zaragoza (orcid)0000-0003-3963-0846 Donat-Vargas, C. Ordovás, J.M. Rodríguez-Artalejo, F. Guallar-Castillón, P. 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina 1011 615 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Medic.Prevent.Salud Públ. 75, 6 (2020), 1126-1133 J. gerontol., Ser. A, biol. sci. med. sci. The journals of gerontology. Series A, Biological sciences and medical sciences 1079-5006 326442 http://zaguan.unizar.es/record/148267/files/texto_completo.pdf Versión publicada 2422233 http://zaguan.unizar.es/record/148267/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:148267 articulos driver 2025-01-15-15:06:05 ARTICLE