Effect of Cashew Nut Consumption on Biomarkers of Copper and Zinc Status in Adolescents with Obesity: A Randomized Controlled Trial

Dias, Thaynan dos Santos ; Almondes, Kaluce G. de S. ; Firmino, Matheus A. D. ; Oliveira, Luis Felipe N. de ; Freire, Walter B. de S. ; Barbosa, Fernando ; Nogueira, Maria Dinara de A. ; Pires, Liliane V. ; Martínez-Vizcaíno, Vicente ; Mesas, Arthur E. ; Moreno, Luis A. (Universidad de Zaragoza) ; Maia, Carla S. C.

Resumen: Background: Children and adolescents with obesity have altered serum copper (Cu) and zinc (Zn) levels, which are associated with oxidative stress, inflammation, and health outcomes. The inclusion of cashew nuts in an adequate diet may provide health benefits and help improve the mineral status of individuals with obesity. Objective: To evaluate the effects of cashew nut consumption on biomarkers of Cu and Zn status in adolescents with obesity. Methods: This was a randomized controlled trial conducted in adolescents. The participants were divided into a control group (CON) and a cashew nut group (CASN). The CASN group received 30 g/day of roasted cashew nuts for 12 weeks, and both groups received nutritional counseling during the study. Anthropometric, dietary, and biochemical parameters (Zn, Cu, and superoxide dismutase (SOD)) were assessed at the baseline and at the end of the study. Association tests, within-group and between-group mean comparisons, and analyses of variation between study periods (Δ T12-T0) were performed. Results: The sample consisted of 81 adolescents who completed the intervention period, resulting in 54 in the CASN group and 27 in the CON group. After the intervention, the CASN group presented a decrease in plasma Cu (p = 0.004) and an increase in SOD (p = 0.030). Both groups showed an increase in plasma Zn (p < 0.050) and a decrease in the Cu/Zn ratio (p < 0.001). CASN had a negative effect on the Cu concentration, which was significantly different from that of CON (p = 0.004). Conclusions: The consumption of cashew nuts for 12 weeks reduced plasma Cu levels in adolescents with obesity. Nutritional counseling may have contributed to the increase in plasma Zn levels in all the study participants.

Idioma: Inglés

DOI: 10.3390/nu17010163

Año: 2024

Publicado en: Nutrients 17, 1 (2024), 163 [16 pp.]
ISSN: 2072-6643

Factor impacto JCR: 5.0 (2024)

Categ. JCR: NUTRITION & DIETETICS rank: 17 / 112 = 0.152 (2024) - Q1 - T1

Factor impacto SCIMAGO: 1.473 - Nutrition and Dietetics (Q1) - Food Science (Q1)

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Enfermería (Dpto. Fisiatría y Enfermería)