000148467 001__ 148467
000148467 005__ 20250117162507.0
000148467 0247_ $$2doi$$a10.1016/j.rce.2015.06.003
000148467 0248_ $$2sideral$$a93248
000148467 037__ $$aART-2015-93248
000148467 041__ $$aspa
000148467 100__ $$0(orcid)0000-0003-1359-6424$$aSáenz-Abad, D.$$uUniversidad de Zaragoza
000148467 245__ $$aImportancia pronóstica de la variabilidad glucémica sobre la mortalidad intrahospitalaria en pacientes ingresados en Medicina Interna
000148467 260__ $$c2015
000148467 5203_ $$aIntroduction The objective was to assess the prognostic importance of various glycaemic control measures on hospital mortality. Material and methods Retrospective, analytical cohort study that included patients hospitalised in internal medicine departments with a diagnosis related to diabetes mellitus (DM), excluding acute decompensations. The clinical endpoint was hospital mortality. We recorded clinical, analytical and glycaemic control-related variables (scheduled insulin administration, plasma glycaemia at admission, HbA1c, mean glycaemia (MG) and in-hospital glycaemic variability and hypoglycaemia). The measurement of hospital mortality predictors was performed using univariate and multivariate logistic regression. Results A total of 384 patients (50.3% men) were included. The mean age was 78.5 (SD, 10.3) years. The DM-related diagnoses were type 2 diabetes (83.6%) and stress hyperglycaemia (6.8%). Thirty-one (8.1%) patients died while in hospital. In the multivariate analysis, the best model for predicting mortality (R2 = 0.326; P<.0001) consisted, in order of importance, of age (¿2 = 8.19; OR = 1.094; 95% CI 1.020-1.174; P=.004), Charlson index (¿2 = 7.28; OR = 1.48; 95% CI 1.11-1.99; P=.007), initial glycaemia (¿2 = 6.05; OR = 1.007; 95% CI 1.001-1.014; P=.014), HbA1c (¿2 = 5.76; OR = 0.59; 95% CI 0.33-1; P=.016), glycaemic variability (¿2 = 4.41; OR = 1.031; 95% CI 1-1.062; P=.036), need for corticosteroid treatment (¿2 = 4.03; OR = 3.1; 95% CI 1-9.64; P=.045), administration of scheduled insulin (¿2 = 3.98; OR = 0.26; 95% CI 0.066-1; P=.046) and systolic blood pressure (¿2 = 2.92; OR = 0.985; 95% CI 0.97-1.003; P=.088). Conclusion An increase in initial glycaemia and in-hospital glycaemic variability predict the risk of mortality for hospitalised patients with DM.
000148467 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000148467 590__ $$a0.76$$b2015
000148467 591__ $$aMEDICINE, GENERAL & INTERNAL$$b105 / 153 = 0.686$$c2015$$dQ3$$eT3
000148467 592__ $$a0.186$$b2015
000148467 593__ $$aMedicine (miscellaneous)$$c2015$$dQ3
000148467 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000148467 700__ $$aGimeno-Orna, J.
000148467 700__ $$0(orcid)0000-0003-2361-9941$$aPérez-Calvo, J. I.$$uUniversidad de Zaragoza
000148467 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000148467 773__ $$g215, 9 (2015), 479-485$$pRev. clín. esp.$$tRevista Clínica Española$$x0014-2565
000148467 8564_ $$s564376$$uhttps://zaguan.unizar.es/record/148467/files/texto_completo.pdf$$yVersión publicada
000148467 8564_ $$s1989699$$uhttps://zaguan.unizar.es/record/148467/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000148467 909CO $$ooai:zaguan.unizar.es:148467$$particulos$$pdriver
000148467 951__ $$a2025-01-17-14:36:23
000148467 980__ $$aARTICLE