148538 20250120165541.0 doi 10.1016/j.canep.2014.05.002 sideral 87697 ART-2014-87697 eng Esteva, M. Age differences in presentation, diagnosis pathway and management of colorectal cancer 2014 BACKGROUND: The gap in survival between older and younger European cancer patients is getting wider. It is possible that cancer in the elderly is being managed or treated differently than in their younger counterparts. This study aims to explore age disparities with respect to the clinical characteristics of the tumour, diagnostic pathway and treatment of colorectal cancer patients. METHODS: We conducted a multicenter cross sectional study in 5 Spanish regions. Consecutive incident cases of CRC were identified from pathology services. MEASUREMENTS: From patient interviews, hospital and primary care clinical records, we collected data on symptoms, stage, doctors investigations, time duration to diagnosis/treatment, quality of care and treatment. RESULTS: 777 symptomatic cases, 154 were older than 80 years. Stage was similar by age group. General symptoms were more frequent in the eldest and abdominal symptoms in the youngest. No differences were found regarding perception of symptom seriousness and symptom disclosure between age groups as no longer duration to diagnosis or treatment was observed in the oldest groups. In primary care, only ultrasound is more frequently ordered in those <65 years. Those >80 years had a significantly higher proportion of iron testing and abdominal XR requested in hospital. We observed a high resection rate independently of age but less adjuvant chemotherapy in Stage III colon cancer, and of radiotherapy in stage II and III rectal cancer as age increases. CONCLUSION: There are no relevant age disparities in the CRC diagnosis process with similar stage, duration to diagnosis, investigations and surgery. However, further improvements have to be made with respect to adjuvant therapy. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/ISCIII/PI050700 info:eu-repo/grantAgreement/ES/ISCIII/PI050787 info:eu-repo/grantAgreement/ES/ISCIII/PI052141 info:eu-repo/grantAgreement/ES/ISCIII/PI052273 info:eu-repo/grantAgreement/ES/ISCIII/PI052692 info:eu-repo/grantAgreement/ES/ISCIII/RD06-0018 info:eu-repo/grantAgreement/ES/ISCIII-RETCI/RD12-0005-0011 info:eu-repo/grantAgreement/ES/ISCIII-RETCI/G03-170 info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 2.711 2014 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 38 / 164 = 0.232 2014 Q1 T1 ONCOLOGY 115 / 209 = 0.55 2014 Q3 T2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Ruiz, A. Ramos, M. Casamitjana, M. Sánchez-Calavera, M.A. Universidad de Zaragoza (orcid)0000-0001-8756-114X González-Luján, L. Pita-Fernández, S. Leiva, A. Pértega-Díaz, S. Costa-Alcaraz, A. Macià, F. Espí, A. Segura, J.M. Lafita, S. Novella, M.T. Yus, C. Oliván, B. Cabeza, E. Seoane-Pillado, T. López-Calviño, B. Llobera, J. Martín-Rabadán, M. Maria Teresa Novella, M. Ripoll, J. Manzano, H. Amengual, I. Forteza, A. Company, M. Lluch Bennassar, Maria de Sánchez, M.A. Magallón, R. Olivan, B. Universidad de Zaragoza (orcid)0000-0001-6565-9699 Maciá, F. Pita, S. Pertega-Díaz, S. Louro, A. Serrano, J. Arnal, F. González-Santamaría, P. Seoane, T. González-Lujan, L. Costa-Alcaraz, A. Espí, I. Bosca, M.M. Balza, N. Villagrasa, R.A. Vázquez,J. F. González-Timoneda, Y.A. 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 4009 740 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Social 38, 4 (2014), 346-353 Cancer Epidemiology Cancer Epidemiology 1877-7821 362266 http://zaguan.unizar.es/record/148538/files/texto_completo.pdf Postprint 2435418 http://zaguan.unizar.es/record/148538/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:148538 articulos driver 2025-01-20-14:52:37 ARTICLE