000148563 001__ 148563
000148563 005__ 20250120165542.0
000148563 0247_ $$2doi$$a10.1186/1471-2407-13-87
000148563 0248_ $$2sideral$$a81924
000148563 037__ $$aART-2013-81924
000148563 041__ $$aeng
000148563 100__ $$aEsteva, M.
000148563 245__ $$aFactors related with symptom duration until diagnosis and treatment of symptomatic colorectal cancer
000148563 260__ $$c2013
000148563 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148563 5203_ $$aBackground
Colorectal cancer (CRC) survival depends mostly on stage at the time of diagnosis. However, symptom duration at diagnosis or treatment have also been considered as predictors of stage and survival. This study was designed to: 1) establish the distinct time-symptom duration intervals; 2) identify factors associated with symptom duration until diagnosis and treatment.
Methods
This is a cross-sectional study of all incident cases of symptomatic CRC during 2006–2009 (795 incident cases) in 5 Spanish regions. Data were obtained from patients’ interviews and reviews of primary care and hospital clinical records. Measurements: CRC symptoms, symptom perception, trust in the general practitioner (GP), primary care and hospital examinations/visits before diagnosis, type of referral and tumor characteristics at diagnosis. Symptom Diagnosis Interval (SDI) was calculated as time from first CRC symptoms to date of diagnosis. Symptom Treatment Interval (STI) was defined as time from first CRC symptoms until start of treatment. Nonparametric tests were used to compare SDI and STI according to different variables.
Results
Symptom to diagnosis interval for CRC was 128 days and symptom treatment interval was 155. No statistically significant differences were observed between colon and rectum cancers. Women experienced longer intervals than men. Symptom presentation such as vomiting or abdominal pain and the presence of obstruction led to shorter diagnostic or treatment intervals. Time elapsed was also shorter in those patients that perceived their first symptom/s as serious, disclosed it to their acquaintances, contacted emergencies services or had trust in their GPs. Primary care and hospital doctor examinations and investigations appeared to be related to time elapsed to diagnosis or treatment.
Conclusions
Results show that gender, symptom perception and help-seeking behaviour are the main patient factors related to interval duration. Health service performance also has a very important role in symptom to diagnosis and treatment interval. If time to diagnosis is to be reduced, interventions and guidelines must be developed to ensure appropriate examination and diagnosis during both primary and hospital care.
000148563 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/PI050700$$9info:eu-repo/grantAgreement/ES/ISCIII/PI050787$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052141$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052273$$9info:eu-repo/grantAgreement/ES/ISCIII/PI052692$$9info:eu-repo/grantAgreement/ES/ISCIII/RD06-0018$$9info:eu-repo/grantAgreement/ES/ISCIII-RETCI/G03-170
000148563 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000148563 590__ $$a3.319$$b2013
000148563 591__ $$aONCOLOGY$$b74 / 203 = 0.365$$c2013$$dQ2$$eT2
000148563 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000148563 700__ $$aLeiva, A.
000148563 700__ $$aRamos, M.
000148563 700__ $$aPita-Fernández, S.
000148563 700__ $$aGonzález-Luján, L.
000148563 700__ $$aCasamitjana, M.
000148563 700__ $$0(orcid)0000-0001-8756-114X$$aSánchez, M. A.$$uUniversidad de Zaragoza
000148563 700__ $$aPértega-Díaz, S.
000148563 700__ $$aRuiz, A.
000148563 700__ $$aGonzalez-Santamaría, P.
000148563 700__ $$aMartín-Rabadán, M.
000148563 700__ $$aCosta-Alcaraz, A.
000148563 700__ $$aEspí, A.
000148563 700__ $$aMacià, F.
000148563 700__ $$aSegura, J. M.
000148563 700__ $$aLafita, S.
000148563 700__ $$aArnal-Monreal, F.
000148563 700__ $$aAmengual, I.
000148563 700__ $$aBoscá-Watts, M. M.
000148563 700__ $$aHospital, A.
000148563 700__ $$aManzano, H.
000148563 700__ $$0(orcid)0000-0002-5494-6550$$aMagallón, R.$$uUniversidad de Zaragoza
000148563 700__ $$aNovella, M. T.
000148563 700__ $$aCabeza, E.
000148563 700__ $$aRipoll, J.
000148563 700__ $$aForteza, A.
000148563 700__ $$aCompany, M.
000148563 700__ $$ade Lluch Bennassar
000148563 700__ $$aLlobera, J.
000148563 700__ $$aOlivan, B.
000148563 700__ $$aYus, C.
000148563 700__ $$aCasamitjana, M.
000148563 700__ $$aPita, S.
000148563 700__ $$aPertega, S.
000148563 700__ $$aLouro, A.
000148563 700__ $$aSerrano, J.
000148563 700__ $$aArnal, F.
000148563 700__ $$aGonzález-Santamaria, P.
000148563 700__ $$aGonzález-Lujan, L.
000148563 700__ $$aBalza, N.
000148563 700__ $$aVillagrasa, R. A.
000148563 700__ $$aVázquez, J. F.
000148563 700__ $$aGonzález-Timoneda, A.
000148563 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000148563 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000148563 773__ $$g13 (2013), 87 [13 pp.]$$pBMC CANCER$$tBMC CANCER$$x1471-2407
000148563 8564_ $$s288463$$uhttps://zaguan.unizar.es/record/148563/files/texto_completo.pdf$$yVersión publicada
000148563 8564_ $$s2154165$$uhttps://zaguan.unizar.es/record/148563/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000148563 909CO $$ooai:zaguan.unizar.es:148563$$particulos$$pdriver
000148563 951__ $$a2025-01-20-14:53:11
000148563 980__ $$aARTICLE