000148695 001__ 148695
000148695 005__ 20250121150753.0
000148695 0247_ $$2doi$$a10.1016/j.vetmic.2018.12.005
000148695 0248_ $$2sideral$$a141785
000148695 037__ $$aART-2018-141785
000148695 041__ $$aeng
000148695 100__ $$0(orcid)0000-0001-7106-0068$$aGarza-Moreno, Laura
000148695 245__ $$aComparison of vaccination protocols against Mycoplasma hyopneumoniae during the gilt acclimation period
000148695 260__ $$c2018
000148695 5060_ $$aAccess copy available to the general public$$fUnrestricted
000148695 5203_ $$aThis study evaluated different gilt vaccination protocols against Mycoplasma (M.) hyopneumoniae at acclimation and their effect on the genetic diversity. A total of 180 M. hyopneumoniae naïve gilts were selected 1 week post-entry (wpe) at the acclimation barn in a clinically affected M. hyopneumoniae farm. Gilts were distributed according to the M. hyopneumoniae antibodies levels into three different vaccination schedules: A) four doses of a M. hyopneumoniae commercial vaccine at 2, 4, 6 and 8 wpe; B) two vaccine doses at 2 and 6 wpe and PBS at 4 and 8 wpe; and C) four PBS doses at the same wpe. Detection of M. hyopneumoniae (rt-PCR) and antibodies (ELISA) were assessed in gilts at 1, 14, 27 and 34 wpe and in 6 of their piglets at weaning. Rt-PCR positive gilts were detected at 14 wpe, being the proportion significantly lower in groups A and B (3/120, 3%) than C (27/60, 45%). Seroconversion was detected at 14 wpe, showing significant differences in percentage of inhibition (PI) between groups A (median 4.9, range 3.1–19.9) and B (5.5, 3.7–13.5), and C (14.3, 3.3–53.2). Gilts remained seropositive over the study and significant differences in PI were detected between groups A and B versus C. All piglets were rt-PCR negative, but the proportion of seropositive piglets coming from vaccinated gilts was significantly higher than the non-vaccinated group. M. hyopneumoniae characterization showed high variability. Hence, gilt vaccination with 2 or 4 doses significantly decreased the pathogen infectious pressure, variability, and provided high antibody levels to gilts and their offspring.
000148695 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000148695 590__ $$a2.791$$b2018
000148695 591__ $$aVETERINARY SCIENCES$$b7 / 141 = 0.05$$c2018$$dQ1$$eT1
000148695 591__ $$aMICROBIOLOGY$$b67 / 133 = 0.504$$c2018$$dQ3$$eT2
000148695 592__ $$a1.166$$b2018
000148695 593__ $$aMedicine (miscellaneous)$$c2018$$dQ1
000148695 593__ $$aVeterinary (miscellaneous)$$c2018$$dQ1
000148695 593__ $$aMicrobiology$$c2018$$dQ1
000148695 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000148695 700__ $$aPieters, Maria
000148695 700__ $$aLópez-Soria, Sergio
000148695 700__ $$aCarmona, Marta
000148695 700__ $$aKrejci, Roman
000148695 700__ $$aSegalés, Joaquim
000148695 700__ $$aSibila, Marina
000148695 773__ $$g229 (2018), 7-13$$pVet. microbiol.$$tVeterinary Microbiology$$x0378-1135
000148695 8564_ $$s216200$$uhttps://zaguan.unizar.es/record/148695/files/texto_completo.pdf$$yPostprint
000148695 8564_ $$s1101555$$uhttps://zaguan.unizar.es/record/148695/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000148695 909CO $$ooai:zaguan.unizar.es:148695$$particulos$$pdriver
000148695 951__ $$a2025-01-21-14:43:36
000148695 980__ $$aARTICLE