000148699 001__ 148699 000148699 005__ 20250122145317.0 000148699 0247_ $$2doi$$a10.1093/ptj/pzaa222 000148699 0248_ $$2sideral$$a124350 000148699 037__ $$aART-2021-124350 000148699 041__ $$aeng 000148699 100__ $$aJiménez Del Barrio, S. 000148699 245__ $$aEffects of Diacutaneous Fibrolysis on Mechanosensitivity, Disability, and Nerve Conduction Studies in Mild to Moderate Carpal Tunnel Syndrome: Secondary Analysis of a Randomized Controlled Trial 000148699 260__ $$c2021 000148699 5060_ $$aAccess copy available to the general public$$fUnrestricted 000148699 5203_ $$aOBJECTIVE: People diagnosed with carpal tunnel syndrome (CTS) have fibrosis between the soft, connective, and neural tissues that could worsen the compression of the median nerve. The diacutaneous fibrolysis (DF) technique may release tissue adhesions and increase the mobility of connective tissues. The purpose of this study was to compare the outcomes of DF in people with mild to moderate CTS on mechanosensitivity, disability, and nerve conduction studies. METHODS: This was a secondary analysis of a double-blinded, randomized, placebo-controlled trial. Patients were recruited between April and September 2016 from the Department of Neurophysiology at the Hospital Miguel Servet, Zaragoza, Spain. Thirty-nine people (52 wrists) diagnosed with mild to moderate CTS were included. Participants were randomly assigned to either the DF group (n = 26) or the sham group (n = 26). Both groups received 5 therapy sessions, 2 sessions per week. Mechanosensitivity with the Upper Limb Neurodynamic Test 1, symptom severity and functional status with the Boston Carpal Tunnel Questionnaire, and median nerve sensory conduction velocity with nerve conduction studies were the outcomes measured. Assessments were recorded at baseline and after the intervention. RESULTS: The DF group showed significant improvements in the following: mechanosensitivity, with 28.46 degrees of elbow extension range of motion (95% CI = 19.2-37.7); an increase of 1.0 point (95% CI = 0.7-1.4) for the Boston Carpal Tunnel Questionnaire symptom severity and functional status score; and sensory conduction velocity of median nerve, which improved to 5.8 m/s (95% CI = 2.5-9.2). CONCLUSION: Participants with mild to moderate CTS experienced improvements in symptom severity, functional status, mechanosensitivity, and nerve conduction studies after 5 sessions of DF. IMPACT: This study provides evidence of an approach based on soft and connective tissues around the median nerve in patients with CTS. 000148699 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000148699 590__ $$a3.679$$b2021 000148699 591__ $$aREHABILITATION$$b15 / 68 = 0.221$$c2021$$dQ1$$eT1 000148699 591__ $$aORTHOPEDICS$$b22 / 86 = 0.256$$c2021$$dQ2$$eT1 000148699 592__ $$a0.881$$b2021 000148699 593__ $$aPhysical Therapy, Sports Therapy and Rehabilitation$$c2021$$dQ1 000148699 594__ $$a4.2$$b2021 000148699 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/submittedVersion 000148699 700__ $$aCeballos-Laita, L. 000148699 700__ $$0(orcid)0000-0002-0026-9224$$aBueno-Gracia, E.$$uUniversidad de Zaragoza 000148699 700__ $$aRodríguez-Marco, S. 000148699 700__ $$aHaddad-Garay, M. 000148699 700__ $$0(orcid)0000-0002-5161-7479$$aEstébanez-de-Miguel, E.$$uUniversidad de Zaragoza 000148699 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia 000148699 773__ $$g101, 2 (2021), pzaa222 [8 pp.]$$pPhys. ther.$$tPhysical Therapy$$x0031-9023 000148699 8564_ $$s735155$$uhttps://zaguan.unizar.es/record/148699/files/texto_completo.pdf$$yPostprint 000148699 8564_ $$s635324$$uhttps://zaguan.unizar.es/record/148699/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000148699 909CO $$ooai:zaguan.unizar.es:148699$$particulos$$pdriver 000148699 951__ $$a2025-01-22-14:52:03 000148699 980__ $$aARTICLE