148922 20250124145431.0 doi 10.1093/cercor/bhaa283 sideral 133955 ART-2021-133955 eng Salillas, Elena Universidad de Zaragoza (orcid)0000-0002-0873-5357 Neurofunctional components of simple calculation: A magnetoencephalography study (*) corresponding author) 2021 Access copy available to the general public Unrestricted Our ability to calculate implies more than the sole retrieval of the correct solution. Essential processes for simple calculation are related to the spreading of activation through arithmetic memory networks. There is behavioral and electrophysiological evidence for these mechanisms. Their brain location is, however, still uncertain. Here, we measured magnetoencephalographic brain activity during the verification of simple multiplication problems. Following the operands, the solutions to verify could be preactivated correct solutions, preactivated table-related incorrect solutions, or unrelated incorrect solutions. Brain source estimation, based on these event-related fields, revealed 3 main brain networks involved in simple calculation: 1) bilateral inferior frontal areas mainly activated in response to correct, matching solutions; 2) a left-lateralized frontoparietal network activated in response to incorrect table-related solutions; and (3) a strikingly similar frontoparietal network in the opposite hemisphere activated in response to unrelated solutions. Directional functional connectivity analyses revealed a bidirectional causal loop between left parietal and frontal areas for table-related solutions, with frontal areas explaining the resolution of arithmetic competition behaviorally. Hence, this study isolated at least 3 neurofunctional networks orchestrated between hemispheres during calculation. info:eu-repo/grantAgreement/EC/H2020/793071/EU/Re-Mapping the Numerical Brain/Re-MAPMATH This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 793071-Re-MAPMATH info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 4.861 2021 NEUROSCIENCES 96 / 275 = 0.349 2021 Q2 T2 2.07 2021 Cognitive Neuroscience 2021 Q1 Cellular and Molecular Neuroscience 2021 Q1 8.7 2021 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Piccione, Francesco Di Tomaso, Silvia Zago, Sara Arcara, Giorgio Semenza, Carlo 4009 730 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Básica 31, 2 (2021), 1162 - 1162 Cereb. cortex CEREBRAL CORTEX 1047-3211 1439563 http://zaguan.unizar.es/record/148922/files/texto_completo.pdf Postprint 708571 http://zaguan.unizar.es/record/148922/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:148922 articulos driver 2025-01-24-14:51:15 ARTICLE