000148936 001__ 148936 000148936 005__ 20250123152145.0 000148936 0247_ $$2doi$$a10.1016/j.rvsc.2025.105541 000148936 0248_ $$2sideral$$a142047 000148936 037__ $$aART-2025-142047 000148936 041__ $$aeng 000148936 100__ $$aAranda, María del Carmen 000148936 245__ $$aA longitudinal study on the detection of anti-Leishmania antibodies in a captive European mink (Mustela lutreola) population and their correlation with serum protein electrophoresis 000148936 260__ $$c2025 000148936 5203_ $$aLeishmaniosis, caused by Leishmania infantum and transmitted by sand flies, is a significant zoonotic disease. Dogs are primary reservoirs, but other domestic animals, such as cats and ferrets, and wild species, including Eurasian otters and European mink, can be hosts. This study focused on European mink, a critically endangered species, investigating the seroprevalence of L. infantum antibodies and its correlation with serum protein profiles over 2021–2024. A total of 68 captive minks in Spain were monitored, yielding 105 serum samples. ELISA tests identified 44 seropositive samples (41.9 %), with seroprevalence varying annually. While no significant association was found between seropositivity and age, gender, or body condition, seropositivity correlated significantly with the year of collection. Some animals exhibited fluctuating antibody levels across sampling periods. Serum protein electrophoresis analyzed 96 samples, revealing that L. infantum seropositivity significantly affected total protein concentrations, β-globulins, γ-globulins, and albumin:globulin ratio. Variations were also observed in specific protein fractions among both seropositive and seronegative minks. These findings highlight European mink's potential epidemiological role in L. infantum transmission. Monitoring antibody levels and protein profiles in captive populations can inform conservation strategies and disease management efforts. 000148936 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000148936 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000148936 700__ $$aVillora, José 000148936 700__ $$aGiner, Jacobo 000148936 700__ $$0(orcid)0000-0002-2557-4890$$aFernández, Antonio$$uUniversidad de Zaragoza 000148936 700__ $$aQuílez, Pablo$$uUniversidad de Zaragoza 000148936 700__ $$aDavies, Janine Elizabeth$$uUniversidad de Zaragoza 000148936 700__ $$aPérez, María D. 000148936 700__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, Sergio$$uUniversidad de Zaragoza 000148936 700__ $$aMarteles, Diana$$uUniversidad de Zaragoza 000148936 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000148936 773__ $$g185 (2025), 105541 [7 pp.]$$pRes. Vet. Sci.$$tRESEARCH IN VETERINARY SCIENCE$$x0034-5288 000148936 8564_ $$s449075$$uhttps://zaguan.unizar.es/record/148936/files/texto_completo.pdf$$yVersión publicada 000148936 8564_ $$s2635590$$uhttps://zaguan.unizar.es/record/148936/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000148936 909CO $$ooai:zaguan.unizar.es:148936$$particulos$$pdriver 000148936 951__ $$a2025-01-23-14:47:23 000148936 980__ $$aARTICLE