doi:10.17352/2455-5282.000190engGimeno Marco, FernandoCastillo Salazar, IsabelDomínguez Almuzara, GabrielTenas Gonzalvo, JavierAra Gimeno, SusanaHernández Jordán, CristinaGutiérrez Pablo, HéctorPie Villacampa, MartaNajarro López, AdriánCarrión Pareja, Juan CarlosCharte Alegre, ElenaAvoidance interoceptive disorder treatment in ankylosing spondylitisART-2025-142098In Ankylosing Spondylitis (AS), sub-axial cervical involvement associated with episodes of neck pain is often observed. The pain and the anticipation of physical damage in these episodes can trigger a conditioned anxiety response with panic attacks, resulting in an Interoceptive Avoidance Disorder (IAD). Using a multiple baseline n=1 between-subjects design, in vivo exposure treatment was implemented using a joint mobility routine and cognitive-behavioral coping strategies in two cases of AS affected by IAD. After 14 weeks, both cases were discharged. During treatment, the efficacy of the in vivo exposure technique used is verified. The possibility of application in other analogous cases, in which the characteristic symptoms of AS act as a trigger for the problem, and the contribution to the reduction of anxious symptoms, justifies the consideration of this treatment for the improvement of the state of health in the EA.2025http://zaguan.unizar.es/record/14896310.17352/2455-5282.000190http://zaguan.unizar.es/record/148963oai:zaguan.unizar.es:148963info:eu-repo/grantAgreement/ES/UZ/PIIDUZ-13-255Global journal of medical and clinical case reports 12, 1 (2025), 001-003byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess