000149056 001__ 149056
000149056 005__ 20251017144636.0
000149056 0247_ $$2doi$$a10.1186/s12889-025-21396-1
000149056 0248_ $$2sideral$$a142148
000149056 037__ $$aART-2025-142148
000149056 041__ $$aeng
000149056 100__ $$aLópez-Ferreruela, Irene
000149056 245__ $$aGender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction
000149056 260__ $$c2025
000149056 5060_ $$aAccess copy available to the general public$$fUnrestricted
000149056 5203_ $$aBackground
European guidelines recommend the prescription of certain drugs after acute myocardial infarction (AMI). The existence of gender differences in pharmacological treatment after an AMI has been described. This study aims to describe and analyse, using real-world data (RWD), whether there are gender differences in the prescribing patterns and initiation of treatment in secondary prevention after a first AMI, and which are the factors that explain these differences.
Methods
A population-based observational study of RWD was conducted in the CARhES (CArdiovascular Risk factors for hEalth Services research) cohort. The study included subjects who had experienced a first episode of AMI between 2017 and 2022, had survived the event, and had a minimum follow-up of 180 days.
Results
3,975 subjects were followed 180 days after a first AMI. Women (27.8% of the study population) were older and had more comorbidities. Of the main guideline-recommended drugs, antiplatelets, lipid modifying agents and beta-blockers, were prescribed less often in women. Comedications such as rivaroxaban and calcium channel blockers were more likely to be prescribed in women. The proportion of subjects initiating treatment was similar in both genders.
Overall, age and morbidity burden were the main contributors to differences in the prescribing patterns. Living in an urban area seemed to be a protective or mitigating factor. There were controversial results regarding socioeconomic level.
Conclusion
In our study population, women are older, have greater comorbidities and lower socioeconomic status. Despite this, gender inequalities in the prescribing patterns after a first AMI remains, as women appear to experience less therapeutic effort. It is crucial to analyse them from an intersectional perspective, considering the influence of multiple axes of inequality on health, in order to develop gender-sensitive strategies with a multidisciplinary approach.
000149056 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/PI22-01193
000149056 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000149056 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000149056 700__ $$0(orcid)0000-0002-7194-8275$$aMalo, Sara$$uUniversidad de Zaragoza
000149056 700__ $$aObón-Azuara, Blanca
000149056 700__ $$0(orcid)0000-0002-6671-5661$$aRabanaque, María José$$uUniversidad de Zaragoza
000149056 700__ $$aGamba, Adriana
000149056 700__ $$0(orcid)0000-0002-5064-3763$$aCastel-Feced, Sara$$uUniversidad de Zaragoza
000149056 700__ $$0(orcid)0000-0001-7293-701X$$aAguilar-Palacio, Isabel$$uUniversidad de Zaragoza
000149056 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera.
000149056 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000149056 773__ $$g25 (2025), 185 [12 pp.]$$pBMC Public Health$$tBMC PUBLIC HEALTH$$x1471-2458
000149056 8564_ $$s1856792$$uhttps://zaguan.unizar.es/record/149056/files/texto_completo.pdf$$yVersión publicada
000149056 8564_ $$s2023543$$uhttps://zaguan.unizar.es/record/149056/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000149056 909CO $$ooai:zaguan.unizar.es:149056$$particulos$$pdriver
000149056 951__ $$a2025-10-17-14:29:29
000149056 980__ $$aARTICLE