000149782 001__ 149782
000149782 005__ 20251017144635.0
000149782 0247_ $$2doi$$a10.3171/2013.6.JNS122445
000149782 0248_ $$2sideral$$a133967
000149782 037__ $$aART-2013-133967
000149782 041__ $$aeng
000149782 100__ $$aDella Puppa, Alessandro
000149782 245__ $$aRight parietal cortex and calculation processing. Intra-operative functional mapping of multiplication and addition.
000149782 260__ $$c2013
000149782 5060_ $$aAccess copy available to the general public$$fUnrestricted
000149782 5203_ $$aObject: The role of parietal areas in number processing is well known. The significance of intraoperative functional mapping of these areas has been only partially explored, however, and only a few discordant data are available in the surgical literature with regard to the right parietal lobe. The purpose of this study was to evaluate the clinical impact of simple calculation in cortical electrostimulation of right-handed patients affected by a right parietal brain tumor.
Methods: Calculation mapping in awake surgery was performed in 3 right-handed patients affected by high-grade gliomas located in the right parietal lobe. Preoperatively, none of the patients presented with calculation deficits. In all 3 cases, after sensorimotor and language mapping, cortical and intraparietal sulcus areas involved in single-digit multiplication and addition calculations were mapped using bipolar electrostimulation.
Results: In all patients, different sites of the right parietal cortex, mainly in the inferior lobule, were detected as being specifically related to calculation (multiplication or addition). In 2 patients the intraparietal sulcus was functionally specific for multiplication. No functional sites for language were detected. All sites functional for calculation were spared during tumor resection, which was complete in all cases without postoperative neurological deficits.
Conclusions: These findings provide intraoperative data in support of an anatomofunctional organization for multiplication and addition within the right parietal area. Furthermore, the study shows the potential clinical relevance of intraoperative mapping of calculation in patients undergoing surgery in the right parietal area. Further and larger studies are needed to confirm these data and assess whether mapped areas are effectively essential for function.
000149782 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000149782 590__ $$a3.227$$b2013
000149782 591__ $$aSURGERY$$b21 / 199 = 0.106$$c2013$$dQ1$$eT1
000149782 591__ $$aCLINICAL NEUROLOGY$$b50 / 191 = 0.262$$c2013$$dQ2$$eT1
000149782 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/submittedVersion
000149782 700__ $$aDe Pellegrin, S.
000149782 700__ $$ad´avella, E.
000149782 700__ $$aGioffre, G.
000149782 700__ $$aMunari, M.
000149782 700__ $$aSaladini, M.
000149782 700__ $$0(orcid)0000-0002-0873-5357$$aSalillas, E.
000149782 700__ $$aSemenza, C.
000149782 773__ $$g119, 5 (2013), 1107 - 1111$$pJ. neurosurg.$$tJournal of neurosurgery$$x0022-3085
000149782 8564_ $$s3936909$$uhttps://zaguan.unizar.es/record/149782/files/texto_completo.pdf$$yPreprint
000149782 8564_ $$s944651$$uhttps://zaguan.unizar.es/record/149782/files/texto_completo.jpg?subformat=icon$$xicon$$yPreprint
000149782 909CO $$ooai:zaguan.unizar.es:149782$$particulos$$pdriver
000149782 951__ $$a2025-10-17-14:29:02
000149782 980__ $$aARTICLE