000149808 001__ 149808
000149808 005__ 20251017144647.0
000149808 0247_ $$2doi$$a10.3390/plants14020235
000149808 0248_ $$2sideral$$a142196
000149808 037__ $$aART-2025-142196
000149808 041__ $$aeng
000149808 100__ $$aSánchez-Hernández, Eva
000149808 245__ $$aBioactive Sesquiterpenoids from Santolina chamaecyparissus L. Flowers: Chemical Profiling and Antifungal Activity Against Neocosmospora Species
000149808 260__ $$c2025
000149808 5060_ $$aAccess copy available to the general public$$fUnrestricted
000149808 5203_ $$aSantolina chamaecyparissus L. (cotton-lavender) is receiving increasing attention due to its potential for modern medicine and is considered both a functional food and nutraceutical. In this work, the phytochemical profile of its flower hydromethanolic extract was investigated by gas chromatography–mass spectrometry, and its applications as a biorational for crop protection were explored against Neocosmospora spp., both in vitro and in planta. The phytochemical profiling analysis identified several terpene groups. Among sesquiterpenoids, which constituted the major fraction (50.4%), compounds featuring cedrane skeleton (8-cedren-13-ol), aromadendrene skeleton (such as (−)-spathulenol, ledol, alloaromadendrene oxide, epiglobulol, and alloaromadendrene), hydroazulene skeleton (ledene oxide, isoledene, and 1,2,3,3a,8,8a-hexahydro-2,2,8-trimethyl-,(3aα,8β,8aα)-5,6-azulenedimethanol), or copaane skeleton (cis-α-copaene-8-ol) were predominant. Additional sesquiterpenoids included longiborneol and longifolene. The monoterpenoid fraction (1.51%) was represented by eucalyptol, (+)-4-carene, endoborneol, and 7-norbornenol. In vitro tests against N. falciformis and N. keratoplastica, two emerging soil phytopathogens, resulted in effective concentration EC90 values of 984.4 and 728.6 μg·mL−1, respectively. A higher dose (3000 μg·mL−1) was nonetheless required to achieve full protection in the in planta tests conducted on zucchini (Cucurbita pepo L.) cv. ‘Diamant F1’ and tomato (Solanum lycopersicum L.) cv. ‘Optima F1’ plants inoculated with N. falciformis by root dipping. The reported data indicate an antimicrobial activity comparable to that of fosetyl-Al and higher than that of azoxystrobin conventional fungicides, thus making the flower extract a promising bioactive product for organic farming and expanding S. chamaecyparissus potential applications.
000149808 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000149808 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000149808 700__ $$aMartín-Gil, Jesús
000149808 700__ $$0(orcid)0000-0002-2535-6914$$aGonzález-García, Vicente
000149808 700__ $$0(orcid)0000-0003-3009-0935$$aCasanova-Gascón, José$$uUniversidad de Zaragoza
000149808 700__ $$0(orcid)0000-0003-2713-2786$$aMartín-Ramos, Pablo
000149808 7102_ $$15011$$2705$$aUniversidad de Zaragoza$$bDpto. CC.Agrar.y Medio Natural$$cÁrea Producción Vegetal
000149808 773__ $$g14, 2 (2025), 235 [20 pp.]$$tPlants$$x2223-7747
000149808 8564_ $$s2070362$$uhttps://zaguan.unizar.es/record/149808/files/texto_completo.pdf$$yVersión publicada
000149808 8564_ $$s2630781$$uhttps://zaguan.unizar.es/record/149808/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000149808 909CO $$ooai:zaguan.unizar.es:149808$$particulos$$pdriver
000149808 951__ $$a2025-10-17-14:34:33
000149808 980__ $$aARTICLE