000149995 001__ 149995 000149995 005__ 20250130182919.0 000149995 0247_ $$2doi$$a10.1097/MAO.0b013e3182804b0f 000149995 0248_ $$2sideral$$a82944 000149995 037__ $$aART-2013-82944 000149995 041__ $$aeng 000149995 100__ $$0(orcid)0000-0001-9372-4267$$aWhyte, J.$$uUniversidad de Zaragoza 000149995 245__ $$aCongenital dehiscence in the posterior semicircular canal 000149995 260__ $$c2013 000149995 5203_ $$aHypothesis: Posterior semicircular canal dehiscence (PSCD) may be of congenital origin. Background: PSCD is characterized by the lack of bone coverage, which results in its lumen being exposed to the meninges of the posterior cranial fossa or to the gulf of the jugular vein. It has an incidence of 0.2%. Its presence has been associated with several well-defined entities, although a congenital origin has not been proven. Methods: We have analyzed, from a macroscopic, microscopic, and radiologic (computed tomography) viewpoint, the right temporal bone of a 32-week-old human fetus that presented a defect in the bone coverage located in the rear. Results: The macroscopic study showed a solution of continuity in the posterior semicircular canal, with elliptic morphology and smooth edges. This defect was 3.4 mm long with a width that varied between 0.67 mm in its apical portion and 1.42 in the basal portion. The radiologic study (computed tomography) showed the absence of bone coverage of the posterior semicircular canal, which was open to the intracranial space in the posterior fossa. Its histologic study showed good bone coverage of this canal at the expense of compact bone tissue. However, at the medial end, there is a lack of bone coverage, resulting in the lumen of the canal being open to the intracranial space. The bone edges of the defect did not present any osteoclast activity. Conclusion: The lack of bone coverage (dehiscence) of the posterior semicircular canal in a 32-week-old fetus suggests a congenital component of bony dehiscences of this canal. Even so, this single finding does not conclusively prove the congenital component, and the dehiscence is a finding that can be part of and not by itself a syndrome. 000149995 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000149995 590__ $$a1.598$$b2013 000149995 591__ $$aOTORHINOLARYNGOLOGY$$b15 / 43 = 0.349$$c2013$$dQ2$$eT2 000149995 591__ $$aCLINICAL NEUROLOGY$$b133 / 191 = 0.696$$c2013$$dQ3$$eT3 000149995 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000149995 700__ $$0(orcid)0000-0002-5494-343X$$aCisneros, A.I.$$uUniversidad de Zaragoza 000149995 700__ $$aMartínez, C. 000149995 700__ $$aGracia-Tello, B. 000149995 700__ $$0(orcid)0000-0002-4263-4023$$aWhyte, A.$$uUniversidad de Zaragoza 000149995 700__ $$aCrovetto, R. 000149995 700__ $$aCrovetto, M. A. 000149995 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana 000149995 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal 000149995 773__ $$g34, 6 (2013), 1134-1137$$pOtol. Neurotol.$$tOTOLOGY & NEUROTOLOGY$$x1531-7129 000149995 8564_ $$s1602352$$uhttps://zaguan.unizar.es/record/149995/files/texto_completo.pdf$$yVersión publicada 000149995 8564_ $$s2594314$$uhttps://zaguan.unizar.es/record/149995/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000149995 909CO $$ooai:zaguan.unizar.es:149995$$particulos$$pdriver 000149995 951__ $$a2025-01-30-16:17:01 000149995 980__ $$aARTICLE