000150479 001__ 150479
000150479 005__ 20250210102456.0
000150479 0247_ $$2doi$$a10.1016/j.jbiomech.2020.109691
000150479 0248_ $$2sideral$$a117418
000150479 037__ $$aART-2020-117418
000150479 041__ $$aeng
000150479 100__ $$0(orcid)0000-0002-8503-9291$$aCilla, M.
000150479 245__ $$aA parametric model for studying the aorta hemodynamics by means of the computational fluid dynamics
000150479 260__ $$c2020
000150479 5060_ $$aAccess copy available to the general public$$fUnrestricted
000150479 5203_ $$aPerturbed aorta hemodynamics, as for the carotid and the coronary artery, has been identified as potential predicting factor for cardiovascular diseases. In this study, we propose a parametric study based on the computational fluid dynamics with the aim of providing information regarding aortic disease. In particular, the blood flow inside a parametrized aortic arch is computed as a function of morphological changes of baseline aorta geometry. Flow patterns, wall shear stress, time average wall shear stress and oscillatory shear index were calculated during the cardiac cycle. The influence of geometrical changes on the hemodynamics and on these variables was evaluated. The results suggest that the distance between inflow and aortic arch and the angle between aortic arch and descending trunk are the most influencing parameters regarding the WSS-related indices while the effect of the inlet diameter seems limited. In particular, an increase of the aforementioned distance produces a reduction of the spatial distribution of the higher values of the time average wall shear stress and of the oscillatory shear index independently on the other two parameters while an increase of the angle produce an opposite effect. Moreover, as expected, the analysis of the wall shear stress descriptors suggests that the inlet diameter influences only the flow intensity. As conclusion, the proposed parametric study can be used to evaluate the aorta hemodynamics and could be also applied in the future, for analyzing pathological cases and virtual situations, such as pre- and/or post-operative cardiovascular surgical states that present enhanced changes in the aorta morphology yet promoting important variations on the considered indexes.
000150479 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000150479 590__ $$a2.712$$b2020
000150479 591__ $$aENGINEERING, BIOMEDICAL$$b57 / 89 = 0.64$$c2020$$dQ3$$eT2
000150479 591__ $$aBIOPHYSICS$$b43 / 71 = 0.606$$c2020$$dQ3$$eT2
000150479 592__ $$a0.825$$b2020
000150479 593__ $$aBiomedical Engineering$$c2020$$dQ1
000150479 593__ $$aBiophysics$$c2020$$dQ1
000150479 593__ $$aSports Science$$c2020$$dQ1
000150479 593__ $$aRehabilitation$$c2020$$dQ1
000150479 593__ $$aOrthopedics and Sports Medicine$$c2020$$dQ1
000150479 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000150479 700__ $$aCasales, M.
000150479 700__ $$0(orcid)0000-0002-0664-5024$$aPeña, E.$$uUniversidad de Zaragoza
000150479 700__ $$0(orcid)0000-0002-8375-0354$$aMartínez, M.A.$$uUniversidad de Zaragoza
000150479 700__ $$0(orcid)0000-0002-0116-2736$$aMalvè, M.
000150479 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est.
000150479 773__ $$g103 (2020), 109691 [12 pp.]$$pJ. biomech.$$tJournal of Biomechanics$$x0021-9290
000150479 8564_ $$s7454275$$uhttps://zaguan.unizar.es/record/150479/files/texto_completo.pdf$$yPostprint
000150479 8564_ $$s2731186$$uhttps://zaguan.unizar.es/record/150479/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000150479 909CO $$ooai:zaguan.unizar.es:150479$$particulos$$pdriver
000150479 951__ $$a2025-02-10-08:26:42
000150479 980__ $$aARTICLE