150582 20260217205605.0 doi 10.1111/opo.13395 sideral 142670 ART-2024-142670 eng Hernández-Andrés, Rosa Randomised trial of three treatments for amblyopia: Vision therapy and patching, perceptual learning and patching alone 2024 Access copy available to the general public Unrestricted AbstractActive vision therapy for amblyopia shows good results, but there is no standard vision therapy protocol. This study compared the results of three treatments, two combining patching with active therapy and one with patching alone, in a sample of children with amblyopia.MethodsTwo protocols have been developed: (a) perceptual learning with a computer game designed to favour the medium‐to‐high spatial frequency‐tuned achromatic mechanisms of parvocellular origin and (b) vision therapy with a specific protocol and 2‐h patching. The third treatment group used patching only. Fifty‐two amblyopic children (aged 4–12 years), were randomly assigned to three monocular treatment groups: 2‐h patching (n = 18), monocular perceptual learning (n = 17) and 2‐h patching plus vision therapy (n = 17). Visual outcomes were analysed after 3 months and compared with a control group (n = 36) of subjects with normal vision.ResultsVisual acuity (VA) and stereoacuity (STA) improved significantly after treatment for the three groups with the best results for patching plus vision therapy, followed by monocular perceptual learning, with patching only least effective. Change in the interocular difference in VA was significant for monocular perceptual learning, followed by patching. Differences in STA between groups were not significant. For VA and interocular differences, the final outcomes were influenced by the baseline VA and interocular difference, respectively, with greater improvements in subjects with poorer initial values.ConclusionsVisual acuity and STA improved with the two most active treatments, that is, vision therapy followed by perceptual learning. Patching alone showed the worst outcome. These results suggest that vision therapy should include monocular accommodative exercises, ocular motility and central fixation exercises where the fovea is more active. info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 2.4 2024 OPHTHALMOLOGY 28 / 99 = 0.283 2024 Q2 T1 0.976 2024 Ophthalmology 2024 Q1 Optometry 2024 Q1 Sensory Systems 2024 Q2 4.9 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Serrano, Miguel Ángel Alacreu-Crespo, Adrián Universidad de Zaragoza (orcid)0000-0002-0633-2810 Luque, María José 4009 680 Universidad de Zaragoza Dpto. Psicología y Sociología Área Person.Eval.Trat.Psicoló. 45, 1 (2024), 31-42 Ophthalmic physiol. opt. OPHTHALMIC AND PHYSIOLOGICAL OPTICS 0275-5408 2122128 http://zaguan.unizar.es/record/150582/files/texto_completo.pdf Versión publicada 2423644 http://zaguan.unizar.es/record/150582/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:150582 articulos driver 2026-02-17-20:46:35 ARTICLE