000150948 001__ 150948
000150948 005__ 20250221105701.0
000150948 0247_ $$2doi$$a10.1080/14767058.2019.1628942
000150948 0248_ $$2sideral$$a112024
000150948 037__ $$aART-2021-112024
000150948 041__ $$aeng
000150948 100__ $$aGonzalez Ballano, Isabel
000150948 245__ $$aPregestational body mass index, trimester-specific weight gain and total gestational weight gain: how do they influence perinatal outcomes?
000150948 260__ $$c2021
000150948 5060_ $$aAccess copy available to the general public$$fUnrestricted
000150948 5203_ $$aObjective: To investigate the association between pregestational body mass index (BMI), total gestational weight gain (GWG) and/or trimester-specific weight gain (GWGT) with adverse maternal or perinatal outcomes (AMPOs).
Material and methods: Maternal clinical characteristics and pregnancy and perinatal outcomes were used to predict AMPOs. The predictive ability of BMI, GWG or GWGT for AMPOs was analyzed using the area under the curve (AUC). Logistic regression models in a univariate and multivariate analysis were performed to estimate the odds ratios (OR) and 95% confidence intervals (CI) to predict maternal outcomes (pregnancy induced hypertension, preeclampsia or gestational diabetes mellitus) and perinatal outcomes (small for gestational age, large for gestational age, 5-min Apgar score, admission to neonatal intensive care unit or umbilical cord pH < 7.15).
Results: Women with AMPOs (n = 293) were younger with higher rate of nulliparity (p < 0.001) and with lower height (p = 0.018) as compared to controls (n = 134). In the univariate study, GWGT in third trimester was associated with double risk of pregnancy induced hypertension (OR 2.00; 95% CI, 1.01–3.97). Nonetheless, third-trimester GWG and total GWG have a negative relationship with gestational diabetes mellitus OR 0.32 (95% CI, 0.18–0.58) and OR 0.35 (95% CI, 0.21–0.59), respectively. Women with greater overall and in second trimester GWG have lower risk of having SGA neonates, OR 0.62 (95% CI, 0.39–0.98) and OR 0.60 (95% CI, 0.37–0.98), respectively. In the multivariate study, pregestational BMI is strongly related to the development of preeclampsia and the area under the curve (AUC) of the combination of pregestational BMI and total weight gain was 0.832 (95% CI, 0.63–0.81) for preeclampsia and 0.719 (95% CI, 0.71–0.94) for gestational diabetes mellitus.
Conclusion: Our results suggest than timing of gestational weight gain influence in maternal and perinatal outcomes. Pregestational BMI is a determinant of preeclampsia, maternal weight gain in the third trimester is a determinant of pregnancy induced hypertension and the increase in total GWG reduces the risk of gestational diabetes mellitus and small for gestational age.
000150948 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000150948 590__ $$a2.323$$b2021
000150948 591__ $$aOBSTETRICS & GYNECOLOGY$$b61 / 85 = 0.718$$c2021$$dQ3$$eT3
000150948 592__ $$a0.61$$b2021
000150948 593__ $$aPediatrics, Perinatology and Child Health$$c2021$$dQ2
000150948 593__ $$aObstetrics and Gynecology$$c2021$$dQ2
000150948 594__ $$a4.0$$b2021
000150948 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000150948 700__ $$0(orcid)0000-0001-9585-0187$$aSavirón Cornudella, Ricardo$$uUniversidad de Zaragoza
000150948 700__ $$0(orcid)0000-0002-3007-302X$$aEsteban Escaño, Luis Mariano
000150948 700__ $$0(orcid)0000-0002-6474-2252$$aSanz Saiz, Gerardo$$uUniversidad de Zaragoza
000150948 700__ $$0(orcid)0000-0002-9048-121X$$aCastán Mateo, Sergio$$uUniversidad de Zaragoza
000150948 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera.
000150948 7102_ $$11003$$2027$$aUniversidad de Zaragoza$$bDpto. Anatom.Histolog.Humanas$$cArea Anatom.Embriol.Humana
000150948 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología
000150948 773__ $$g34, 8 (2021), 1207-1214$$pJ. matern.-fetal neonatal med.$$tJournal of Maternal-Fetal and Neonatal Medicine$$x1476-7058
000150948 8564_ $$s1494899$$uhttps://zaguan.unizar.es/record/150948/files/texto_completo.pdf$$yVersión publicada
000150948 8564_ $$s1061259$$uhttps://zaguan.unizar.es/record/150948/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000150948 909CO $$ooai:zaguan.unizar.es:150948$$particulos$$pdriver
000150948 951__ $$a2025-02-21-09:50:57
000150948 980__ $$aARTICLE