150966 20251017144606.0 doi 10.1016/j.lwt.2021.112158 sideral 125784 ART-2021-125784 eng Kaanin-Boudraa G. Response surface methodology and UPLC-QTOF-MSE analysis of phenolic compounds from grapefruit (Citrus¿ paradisi) by-products as novel ingredients for new antioxidant packaging 2021 Access copy available to the general public Unrestricted The present work reports an experimental study on the optimization of phenolic compounds extraction from Citrus ¿ paradisi peels and the development of active packaging. Response surface methodology (RSM) was applied to investigate the effect of microwave-assisted extraction (MAE) for the recovery of total phenolic compounds (TPC). The TPC in the optimized extract were 31.10 mg gallic acid equivalent/100 g of dry weight (mg GAE/100 g dw) with strong antioxidant capacity. The bioactive compounds in the optimized extract were determined by ultrahigh performance liquid chromatography coupled to quadrupole time-of-flight with high energy mass spectrometry (UPLC-QTOF-MSE). Forty-five compounds were detected and qualified. The optimized extract obtained by MAE was used as an active antioxidant in multilayer food packaging films. The multilayer low-density polyethylene (LDPE)/polyethylene terephthalate (PET) containing 10% of MAE optimized extract provided the most antioxidant power acting as a free radical scavenger. © 2021 Elsevier Ltd info:eu-repo/grantAgreement/ES/DGA-FSE/T53-20R info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 6.056 2021 FOOD SCIENCE & TECHNOLOGY 29 / 144 = 0.201 2021 Q1 T1 1.059 2021 Food Science 2021 Q1 7.3 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Brahmi F. Wrona M. Universidad de Zaragoza (orcid)0000-0003-2052-3012 Nerín C. Universidad de Zaragoza (orcid)0000-0003-2685-5739 Moudache M. Mouhoubi K. Madani K. Boulekbache-Makhlouf L. 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 151 (2021), 112158 [11 pp.] Lebensm.-Wiss. Technol. LWT-FOOD SCIENCE AND TECHNOLOGY 0023-6438 2448427 http://zaguan.unizar.es/record/150966/files/texto_completo.pdf Versión publicada 2611766 http://zaguan.unizar.es/record/150966/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:150966 articulos driver 2025-10-17-14:15:33 ARTICLE