150967 20251017144609.0 doi 10.3390/vaccines9111321 sideral 125373 ART-2021-125373 eng Iguacel, Isabel Universidad de Zaragoza (orcid)0000-0003-4242-5464 Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain 2021 Access copy available to the general public Unrestricted COVID-19 vaccines have shown high efficacy, with most side effects being mild-moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever \u226538\u00b0, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to preventrelieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever \u226538\u00b0, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age. info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 4.961 2021 MEDICINE, RESEARCH & EXPERIMENTAL 59 / 139 = 0.424 2021 Q2 T2 IMMUNOLOGY 77 / 162 = 0.475 2021 Q2 T2 1.004 2021 Drug Discovery 2021 Q1 Pharmacology 2021 Q1 Infectious Diseases 2021 Q1 Immunology 2021 Q1 4.5 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Luna Maldonado, Aurelio Luna Ruiz-Cabello, Aurelio Casaus, Marta Moreno, Luis Alberto Universidad de Zaragoza (orcid)0000-0003-0454-653X Martínez-Jarreta, Begoña Universidad de Zaragoza (orcid)0000-0001-6469-9189 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 1012 613 Universidad de Zaragoza Dpto. Farmac.Fisiol.y Med.L.F. Área Medicina Legal y Forense 9, 11 (2021), 1321 [12 pp.] Vaccines 2076-393X 281061 http://zaguan.unizar.es/record/150967/files/texto_completo.pdf Versión publicada 2667209 http://zaguan.unizar.es/record/150967/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:150967 articulos driver 2025-10-17-14:16:23 ARTICLE