000151029 001__ 151029
000151029 005__ 20250221105702.0
000151029 0247_ $$2doi$$a10.1007/s40618-021-01696-0
000151029 0248_ $$2sideral$$a128457
000151029 037__ $$aART-2022-128457
000151029 041__ $$aeng
000151029 100__ $$aCorripio-Collado, R.
000151029 245__ $$aDelphi consensus on the diagnosis and treatment of patients with short stature in Spain: GROW-SENS study; 34791604
000151029 260__ $$c2022
000151029 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151029 5203_ $$aPurpose: To identify consensus aspects related to the diagnosis, monitoring, and treatment of short stature in children to promote excellence in clinical practice. Methods: Delphi consensus organised in three rounds completed by 36 paediatric endocrinologists. The questionnaire consisted of 26 topics grouped into: (1) diagnosis; (2) monitoring of the small-for-gestational-age (SGA) patient; (3) growth hormone treatment; and (4) treatment adherence. For each topic, different questions or statements were proposed. Results: After three rounds, consensus was reached on 16 of the 26 topics. The main agreements were: (1) diagnosis tests considered as a priority in Primary Care were complete blood count, biochemistry, thyroid profile, and coeliac disease screening. The genetic test with the greatest diagnostic value was karyotyping. The main criterion for initiating a diagnostic study was prediction of adult stature 2 standard deviations below the target height; (2) the main criterion for initiating treatment in SGA patients was the previous growth pattern and mean parental stature; (3) the main criterion for response to treatment was a significant increase in growth velocity and the most important parameter to monitor adverse events was carbohydrate metabolism; (4) the main attitude towards non-responding patients is to check their treatment adherence with recording devices. The most important criterion for choosing the delivery device was its technical characteristics. Conclusions: This study shows the different degrees of consensus among paediatric endocrinologists in Spain concerning the diagnosis and treatment of short stature, which enables the identification of research areas to optimise the management of such patients. © 2021, The Author(s).
000151029 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000151029 590__ $$a5.4$$b2022
000151029 591__ $$aENDOCRINOLOGY & METABOLISM$$b34 / 144 = 0.236$$c2022$$dQ1$$eT1
000151029 592__ $$a0.996$$b2022
000151029 593__ $$aEndocrinology, Diabetes and Metabolism$$c2022$$dQ2
000151029 593__ $$aEndocrinology$$c2022$$dQ2
000151029 594__ $$a8.1$$b2022
000151029 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151029 700__ $$aFernández-Ramos, C.
000151029 700__ $$aGonzález-Casado, I.
000151029 700__ $$aMoreno-Macián, F.
000151029 700__ $$aLópez-Siguero, J.P.
000151029 700__ $$0(orcid)0000-0003-2832-2266$$aLabarta-Aizpún, J. -I$$uUniversidad de Zaragoza
000151029 7102_ $$11011$$2670$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Pediatría
000151029 773__ $$g45 (2022), 887-897$$pJ. endocrinol. investig.$$tJournal of endocrinological investigation$$x0391-4097
000151029 8564_ $$s493153$$uhttps://zaguan.unizar.es/record/151029/files/texto_completo.pdf$$yVersión publicada
000151029 8564_ $$s2121459$$uhttps://zaguan.unizar.es/record/151029/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151029 909CO $$ooai:zaguan.unizar.es:151029$$particulos$$pdriver
000151029 951__ $$a2025-02-21-09:52:50
000151029 980__ $$aARTICLE