000151048 001__ 151048
000151048 005__ 20251017144630.0
000151048 0247_ $$2doi$$a10.1016/j.cmpb.2022.106868
000151048 0248_ $$2sideral$$a128729
000151048 037__ $$aART-2022-128729
000151048 041__ $$aeng
000151048 100__ $$0(orcid)0000-0001-8219-2365$$aCabeza-Gil, I.$$uUniversidad de Zaragoza
000151048 245__ $$aPredicting the biomechanical stability of IOLs inside the postcataract capsular bag with a finite element model: Predicting the IOL position after cataract surgery
000151048 260__ $$c2022
000151048 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151048 5203_ $$aBackground and Objectives: Although cataract surgery is a safe operation in developed countries, there is still room for improvement in terms of patient satisfaction. One of the key issues is assessing the biomechanical stability of the IOL within the capsular bag to avoid refractive errors that lead to a second surgery. For that purpose, a numerical model was developed to predict IOL position inside the capsular bag in the short- and long-term. Methods: A finite element model containing the implanted IOL, the postcataract capsular bag, the zonules, and a portion of the ciliary body was designed. The C-loop hydrophobic LUCIA IOL was used to validate the numerical model and two more worldwide IOL designs were tested: the double C-loop hydrophobic POD FT IOL and the plate hydrophilic AT LISA IOL. To analyze the biomechanical stability in the long-term, the effect of the fusion footprint, which occurs days following cataract surgery, was simulated. Moreover, several scenarios were analyzed: the size and location of the capsulorexhis, the capsular bag diameter, the initial geometry of the capsular bag, and the material properties of the bag. Results: The biomechanical stability of the LUCIA IOL was simulated and successfully compared with the in vitro results. The plate AT LISA design deformed the capsular bag diameter up to 11.0 mm against 10.5 mm for the other designs. This design presented higher axial displacement and lower rotation, 0.19 mm and 0.2°, than the C-loop design, 0.09 mm and 0.9°. Conclusions: All optomechanical biomarkers were optimal, assuring good optical performance of the three IOLs under investigation. Our findings showed that the capsulorexhis size influences the stiffness of the capsular bag; however, the shape in the anterior and posterior curvature surfaces of the bag barely affect. The results also suggested that the IOL is prone to mechanical perturbations with the fusion footprint, but they were not high enough to produce a significant refractive error. The proposed model could be a breakthrough in the selection of haptic design according to patient criteria.
000151048 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/T24-20R$$9info:eu-repo/grantAgreement/ES/MCIU/DPI2017-84047-R$$9info:eu-repo/grantAgreement/ES/MICIU/PRE2018-084021
000151048 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000151048 590__ $$a6.1$$b2022
000151048 591__ $$aCOMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS$$b25 / 110 = 0.227$$c2022$$dQ1$$eT1
000151048 591__ $$aMEDICAL INFORMATICS$$b7 / 31 = 0.226$$c2022$$dQ1$$eT1
000151048 591__ $$aENGINEERING, BIOMEDICAL$$b22 / 96 = 0.229$$c2022$$dQ1$$eT1
000151048 591__ $$aCOMPUTER SCIENCE, THEORY & METHODS$$b15 / 111 = 0.135$$c2022$$dQ1$$eT1
000151048 592__ $$a1.118$$b2022
000151048 593__ $$aComputer Science Applications$$c2022$$dQ1
000151048 593__ $$aSoftware$$c2022$$dQ1
000151048 593__ $$aHealth Informatics$$c2022$$dQ1
000151048 594__ $$a10.1$$b2022
000151048 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151048 700__ $$0(orcid)0000-0001-9713-1813$$aCalvo, B.$$uUniversidad de Zaragoza
000151048 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est.
000151048 773__ $$g221 (2022), 106868 [10 pp.]$$pComput. methods programs biomed.$$tComputer Methods and Programs in Biomedicine$$x0169-2607
000151048 8564_ $$s2814973$$uhttps://zaguan.unizar.es/record/151048/files/texto_completo.pdf$$yVersión publicada
000151048 8564_ $$s2517472$$uhttps://zaguan.unizar.es/record/151048/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151048 909CO $$ooai:zaguan.unizar.es:151048$$particulos$$pdriver
000151048 951__ $$a2025-10-17-14:26:12
000151048 980__ $$aARTICLE