000151121 001__ 151121 000151121 005__ 20251017144605.0 000151121 0247_ $$2doi$$a10.1016/j.tjog.2020.11.018 000151121 0248_ $$2sideral$$a122622 000151121 037__ $$aART-2021-122622 000151121 041__ $$aeng 000151121 100__ $$aGuarga Montori, M. 000151121 245__ $$aAdvanced maternal age and adverse pregnancy outcomes: A cohort study 000151121 260__ $$c2021 000151121 5060_ $$aAccess copy available to the general public$$fUnrestricted 000151121 5203_ $$aObjectives: To assess the association between advanced maternal age and adverse perinatal outcomes in single pregnancies. Materials and methods: A cohort study was conducted using data from 27, 455 singleton births attended at our hospital between 2007 and 2018. Three maternal age groups were established, and perinatal outcomes were compared between-groups (<35 years (n = 19, 429; 70.7%), 35–40 years (n = 7189; 26.2%), and >40 years (n = 846; 3.1%). The data were compared using chi-square analysis and the results were adjusted using a logistic regression model. Decision trees were designed to examine the fetal mortality and caesarean section variables. We used the SPSS 23 statistical software program for the statistical analysis. Results: The mean age of the women was 31.21 years. No differences were found associated with age for neonatal acidosis, an Apgar score <7 at 5 min after birth, threatened preterm labour, preterm rupture of membranes, or high-grade perineal tear. The analyses found statistically significant increases in the rates of hypertensive disorders, diabetes mellitus, induction of labour, and caesarean section, after 35 years of age. The risks of fetal death, neonatal admission, small for gestational age, placenta previa, instrument delivery, maternal ICU admission, and postpartum haemorrhage were greater after 40 years of age. Conclusions: The results of our study indicated that women >35 years of age had worse perinatal outcomes, compared with younger women. This finding was more evident in patients >40 years of age, which highlighted the greater risk of fetal death and serious maternal complications in this group. 000151121 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 000151121 590__ $$a1.944$$b2021 000151121 591__ $$aOBSTETRICS & GYNECOLOGY$$b72 / 85 = 0.847$$c2021$$dQ4$$eT3 000151121 592__ $$a0.413$$b2021 000151121 593__ $$aObstetrics and Gynecology$$c2021$$dQ3 000151121 594__ $$a2.7$$b2021 000151121 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000151121 700__ $$aÁlvarez Martínez, A. 000151121 700__ $$aLuna Álvarez, C. 000151121 700__ $$0(orcid)0000-0003-1330-775X$$aAbadía Cuchí, N. 000151121 700__ $$0(orcid)0000-0002-2218-5240$$aMateo Alcalá, P.$$uUniversidad de Zaragoza 000151121 700__ $$aRuiz-Martínez, S.$$uUniversidad de Zaragoza 000151121 7102_ $$11013$$2645$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Obstetricia y Ginecología 000151121 773__ $$g60, 1 (2021), 119-124$$pTaiwan. j. obstet. gynecol.$$tTAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY$$x1028-4559 000151121 8564_ $$s878777$$uhttps://zaguan.unizar.es/record/151121/files/texto_completo.pdf$$yVersión publicada 000151121 8564_ $$s2413594$$uhttps://zaguan.unizar.es/record/151121/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000151121 909CO $$ooai:zaguan.unizar.es:151121$$particulos$$pdriver 000151121 951__ $$a2025-10-17-14:15:05 000151121 980__ $$aARTICLE