doi:10.3390/nu13093035engHermenegildo-López Y.Donat-Vargas C.Sandoval-Insausti H.Moreno-Franco B.Rodríguez-Ayala M.Rey-García J.Banegas J.R.Rodríguez-Artalejo F.Guallar-Castillón P.A higher intake of energy at dinner is associated with incident metabolic syndrome: A prospective cohort study in older adultsART-2021-125825A higher energy intake (EI) at night has been associated with a higher risk of obesity, while a higher EI at lunch may protect against weight gain. This study examined the association between EI throughout the day and incident metabolic syndrome (MetS) among older adults. A cohort of 607 individuals aged = 60 free from MetS at baseline was followed from 2008–2010 until 2015. At baseline, habitual EI was assessed on six eating occasions: breakfast, mid-morning snack, lunch, afternoon snack, dinner, and snacking. MetS was defined according to the harmonized defi-nition. Statistical analyses were performed with logistic regression and adjusted for the main con-founders, including total EI, diet quality, and physical activity/sedentary behavior. During follow-up, 101 new MetS cases occurred. Compared to the lowest sex-specific quartile of EI at dinner, the OR (95% confidence interval) for incident MetS were: 1.71 (0.85–3.46) in the second, 1.70 (0.81–3.54) in the third, and 2.57 (1.14–5.79) in the fourth quartile (p-trend: 0.034). Elevated waist circumference and triglycerides were the MetS components that most contributed to this association. A higher EI at dinner was associated with a higher risk of MetS in older adults. Reducing EI at dinner might be a simple strategy to prevent MetS.2021http://zaguan.unizar.es/record/15114110.3390/nu13093035http://zaguan.unizar.es/record/151141oai:zaguan.unizar.es:151141info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FSE/FIS/PI17-1709info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FSE/FIS/19-319info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FSE/FIS/19-665info:eu-repo/grantAgreement/ES/ISCIII-FEDER-FSE/FIS/20-00144Nutrients 13, 9 (2021), 3035 [11 pp.]byhttps://creativecommons.org/licenses/by/4.0/deed.esinfo:eu-repo/semantics/openAccess