000151154 001__ 151154
000151154 005__ 20251017144608.0
000151154 0247_ $$2doi$$a10.3390/ani11071984
000151154 0248_ $$2sideral$$a124786
000151154 037__ $$aART-2021-124786
000151154 041__ $$aeng
000151154 100__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, Sergio$$uUniversidad de Zaragoza
000151154 245__ $$aAbsence of SARS-CoV-2 Antibodies in Natural Environment Exposure in Sheep in Close Contact with Humans
000151154 260__ $$c2021
000151154 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151154 5203_ $$aSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the zoonotic causative agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic situation with millions of infected humans worldwide. Among domestic animals, there have been limited studies regarding the transmissibility and exposure to the infection in natural conditions. Some animals are exposed andor susceptible to SARS-CoV-2 infection, such as cats, ferrets and dogs. By contrast, there is no information about the susceptibility of ruminants to SARS-CoV-2. This study tested the antibody response in 90 ovine pre-pandemic serum samples and 336 sheep serum samples from the pandemic period (June 2020 to March 2021). In both cases, the animals were in close contact with a veterinary student community composed of more than 700 members. None of the serum samples analyzed was seroreactive based on an enzyme-linked immunosorbent assay (ELISA) using the receptor-binding domain (RBD) of the spike antigen. In this sense, no statistical difference was observed compared to the pre-pandemic sheep. Our results suggest that it seems unlikely that sheep could play a relevant role in the epidemiology of SARS-CoV-2 infection. This is the first study to report the absence of evidence of sheep exposure to SARS-CoV-2 in natural conditions.
000151154 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/COV20-0030
000151154 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000151154 590__ $$a3.231$$b2021
000151154 591__ $$aVETERINARY SCIENCES$$b16 / 145 = 0.11$$c2021$$dQ1$$eT1
000151154 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b13 / 62 = 0.21$$c2021$$dQ1$$eT1
000151154 592__ $$a0.61$$b2021
000151154 593__ $$aVeterinary (miscellaneous)$$c2021$$dQ1
000151154 593__ $$aAnimal Science and Zoology$$c2021$$dQ1
000151154 594__ $$a2.7$$b2021
000151154 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151154 700__ $$aGiner, Jacobo
000151154 700__ $$aFernández, Antonio
000151154 700__ $$0(orcid)0000-0002-7822-6646$$aLacasta, Delia$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-0313-5926$$aOrtín, Aurora$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-2724-2785$$aRamos, Juan José$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0003-0042-8800$$aFerrer, Luis Miguel$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-7655-2472$$aRuiz de Arcaute, Marta$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-2646-5733$$aTobajas, Ana Pilar$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0003-2555-8425$$aPérez, María Dolores$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0003-2957-1379$$aVerde, Maite$$uUniversidad de Zaragoza
000151154 700__ $$aMarteles, Diana
000151154 700__ $$0(orcid)0000-0002-3122-9401$$aHurtado-Guerrero, Ramón
000151154 700__ $$0(orcid)0000-0003-0154-0730$$aPardo, Julián$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-1861-5981$$aSantiago, Llipsy$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-5838-0857$$aGonzález-Ramírez, Andrés Manuel$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0001-6815-6720$$aMacías-León, Javier$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0003-3791-2997$$aGarcía-García, Ana$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0001-9224-5854$$aTaleb, Víctor$$uUniversidad de Zaragoza
000151154 700__ $$aLira-Navarrete, Erandi$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-9600-8116$$aPaño-Pardo, José Ramón$$uUniversidad de Zaragoza
000151154 700__ $$0(orcid)0000-0002-8474-2831$$aRuíz, Héctor$$uUniversidad de Zaragoza
000151154 7102_ $$11011$$2566$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Inmunología
000151154 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000151154 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000151154 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000151154 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos
000151154 773__ $$g11, 7 (2021), 1984 [9 pp.]$$pAnimals (Basel)$$tAnimals$$x2076-2615
000151154 8564_ $$s261469$$uhttps://zaguan.unizar.es/record/151154/files/texto_completo.pdf$$yVersión publicada
000151154 8564_ $$s3014326$$uhttps://zaguan.unizar.es/record/151154/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151154 909CO $$ooai:zaguan.unizar.es:151154$$particulos$$pdriver
000151154 951__ $$a2025-10-17-14:16:16
000151154 980__ $$aARTICLE